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首页> 外文期刊>Comparative Medicine >Hypertrophic Cardiomyopathy in Owl Monkeys (Aotus spp.)
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Hypertrophic Cardiomyopathy in Owl Monkeys (Aotus spp.)

机译：猫头鹰猴肥大型心肌病（Aotus spp。）

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摘要

Cardiac hypertrophy is a common postmortem finding in owl monkeys. In most cases the animals do not exhibit clinical signs until the disease is advanced, making antemortem diagnosis of subclinical disease difficult and treatment unrewarding. We obtained echocardiograms, electrocardiograms, and thoracic radiographs from members of a colony of owl monkeys that previously was identified as showing a 40% incidence of gross myocardial hypertrophy at necropsy, to assess the usefulness of these modalities for antemortem diagnosis. No single modality was sufficiently sensitive and specific to detect all monkeys with cardiac hypertrophy. Electrocardiography was the least sensitive method for detecting owl monkeys with hypertrophic cardiomyopathy. Thoracic radiographs were more sensitive than was electrocardiography in this context but cannot detect animals with concentric hypertrophy without an enlarged cardiac silhouette. Echocardiography was the most sensitive method for identifying cardiac hypertrophy in owl monkeys. The most useful parameters suggestive of left ventricular hypertrophy in our owl monkeys were an increased average left ventricular wall thickness to chamber radius ratio and an increased calculated left ventricular myocardial mass. Parameters suggestive of dilative cardiomyopathy were an increased average left ventricular myocardial mass and a decreased average ratio of left ventricular free wall thickness to left ventricular chamber radius. When all 4 noninvasive diagnostic modalities (physical examination, echocardiography, electrocardiography, and thoracic radiography) were used concurrently, the probability of detecting hypertrophic cardiomyopathy in owl monkeys was increased greatly.
机译：心脏肥大是在猫头鹰猴子中常见的死后发现。在大多数情况下，直到疾病进展，动物才表现出临床体征，这使得亚临床疾病的死前诊断变得困难，治疗无益。我们从猫头鹰猴子的一个殖民地成员那里获得了超声心动图，心电图和胸片，这些东西先前被确定在尸检时显示出40％的总心肌肥大发生率，以评估这些方式对死前诊断的有用性。没有任何一种方法能够足够灵敏和特异地检测所有患有心脏肥大的猴子。心电图检查是检测肥厚型心肌病猫头鹰猫头鹰的最不敏感方法。在这种情况下，胸片比心电图更为灵敏，但如果没有扩大的心脏轮廓，则无法检测出具有同心肥大的动物。超声心动图是识别猫头鹰猴子心脏肥大的最灵敏方法。提示猫头鹰猫头鹰左心室肥大的最有用参数是平均左心室壁厚与室半径之比增加以及计算出的左心室心肌质量增加。提示扩张性心肌病的参数是左室平均心肌质量增加和左室自由壁厚度与左室半径的平均比值降低。同时使用所有四种无创诊断方法（体格检查，超声心动图，心电图和胸腔放射照相）时，在猫头鹰猴中发现肥厚型心肌病的可能性大大增加。

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