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Granuloma Due to Oxidized Regenerated Cellulose in an Aged Rhesus Macaque (Macaca mulatta)

机译:老化恒河猴(Macaca mulatta)中氧化再生纤维素引起的肉芽肿

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摘要

Bioabsorbable hemostatic agents such as oxidized regenerated cellulose are widely used to control intraoperative diffuse capillary bleeding. Compared with electrocautery or ligation, oxidized regenerated cellulose has the advantage of controlling bleeding without occluding the vessel lumen or causing thermal injuries to adjacent tissue. Although the manufacturer recommends removal of the material once hemostasis is achieved, oxidized regenerated cellulose is a bioabsorbable hemostatic agent and is often left in the surgical bed to prevent subsequent bleeding after surgical closure. However, noninvasive imaging techniques have revealed granulomatous foreign-body reactions that mimic infection or tumor recurrence. We present a case report of sterile peritonitis and granuloma formation secondary to the presence of oxidized regenerated cellulose after intestinal resection to excise a colonic adenocarcinoma in an aged rhesus macaque.
机译:可生物吸收的止血剂,例如氧化再生纤维素,被广泛用于控制术中弥散性毛细血管出血。与电灼术或结扎术相比,氧化再生纤维素具有控制出血而不阻塞血管腔或对相邻组织造成热损伤的优点。尽管制造商建议在止血后去除材料,但氧化的再生纤维素是一种可生物吸收的止血剂,通常留在手术床上以防止手术结束后再次出血。但是,非侵入性成像技术已揭示出肉芽肿异物反应,可模仿感染或肿瘤复发。我们提出了不育性腹膜炎和肉芽肿形成的病例报告,继发于小肠恒河猴切除结肠切除后的氧化再生纤维素存在之后,继发了氧化性再生纤维素。

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