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Aspects of common marmoset basic biology and life history important for biomedical research

机译:mar猴的基本生物学和生活史对生物医学研究很重要

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While common marmosets are increasingly used as alternative primate models in biomedical research, their life history, specialized behavior and unique physiology are not well known. This paper describes important marmoset attributes that are particularly relevant for biomedical research, including reproduction, neurobiology, immunology, endocrine signaling, obesity and aging, in addition to fetal and postnatal development. While common marmosets exhibit characteristic anthropoid primate traits, they clearly differ from Old World primates and humans in a variety of functions, including reproduction, endocrine signaling and immunology. These differences, however, permit the use of common marmosets in unconventional research strategies targeted on human pathology.
机译:尽管普通mar猴在生物医学研究中越来越多地被用作灵长类动物的替代模型,但它们的生活史,特殊行为和独特的生理学却并不为人所知。本文介绍了重要的mar猴属性,这些属性与生物医学研究特别相关,包括生殖,神经生物学,免疫学,内分泌信号传导,肥胖和衰老,以及胎儿和产后发育。普通mar猴具有独特的类人猿灵长类特征,但它们与旧世界的灵长类和人类在各种功能(包括生殖,内分泌信号传导和免疫学)方面明显不同。但是,这些差异允许在常规的针对人类病理学的研究策略中使用普通common猴。

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