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Information systems for biobanks/biorepositories: Handling information associated with compliant sample management

机译:生物库/生物库信息系统:处理与合规样本管理相关的信息

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摘要

The first article in this series emphasized the need for good storage practice (GSP)~1 and reiterated that valuable samples are often stored in an ad hoc manner without standardized processes. Storage facilities often lack the robust and scalable information systems necessary to delineate collections and maximize their use in current and future research. It was also recognized that in order for GSP to meet the FDA standards of good tissue practice (GTP), there is a need for clear documentation showing the significant steps in the handling of specimens, including their accessioning (i.e. registration and logging in of samples), storage and retrieval. Informatics systems are also required to manage sample processing, quality control (QC) data and temperature data ranging from ambient to vapor phase liquid nitrogen.
机译:本系列的第一篇文章强调了良好存储规范(GSP)〜1的必要性,并重申有价值的样品通常以临时方式存储,而没有标准化流程。存储设施通常缺乏描述集合并最大化其在当前和未来研究中使用所必需的健壮和可扩展的信息系统。人们还认识到,为了使GSP符合FDA良好组织规范(GTP)的标准,需要有清晰的文件,以显示处理样品的重要步骤,包括样品的加入(即样品的注册和登录)。 ),存储和检索。还需要信息系统来管理样品处理,质量控制(QC)数据和温度数据,范围从环境到气相液相氮。

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