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首页> 外文期刊>Clinical and experimental ophthalmology >Methodology and early findings of the Diabetes Management Project: A cohort study investigating the barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy
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Methodology and early findings of the Diabetes Management Project: A cohort study investigating the barriers to optimal diabetes care in diabetic patients with and without diabetic retinopathy

机译:糖尿病管理项目的方法论和早期发现:一项队列研究,研究了有和没有糖尿病性视网膜病的糖尿病患者获得最佳糖尿病护理的障碍

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Abstract: Background: The Diabetes Management Project is investigating the clinical, behavioural and psychosocial barriers to optimal diabetes care in individuals with and without diabetic retinopathy. Design: Prospective cohort. Participants: Two hundred and twenty-three and 374 patients without and with diabetic retinopathy, respectively. Methods: All individuals underwent a comprehensive dilated eye test, anthropometric measurements, blood and urine samples, and psychosocial questionnaires. Main Outcome Measures: Good glycaemic control was defined as glycosylated haemoglobin<7%, good blood pressure control as systolic and diastolic values ≤130 and 80mmHg, respectively, and good diabetes control as glycosylated haemoglobin<7% and blood pressure values ≤130 and 80mmHg. Results: Four hundred and one males (65.4%) and 212 females (34.6%) aged 26-90years (mean age±standard deviation=64.6±11.6) were examined. The median glycosylated haemoglobin for all participants was 7.5% (interquartile range=1.7%). Average systolic and diastolic blood pressure values were 139.7mmHg (standard deviation=18.8) and 92.7mmHg (standard deviation=30.9), respectively. Initial data analyses indicate that over two-thirds of participants with diabetes have poor glycaemic control, which was worse in those with diabetic retinopathy compared with those without (76.3% vs. 49.3%; P<0.001). Blood pressure control was similar for those with and without diabetic retinopathy, with almost a third (28.5%) of the total sample having poor blood pressure control. Overall, those with diabetic retinopathy had poorer diabetes control than those without (24.3% vs. 13.7%; P=0.002). Conclusions: Our findings substantiate the implementation of the Diabetes Management Project, developed to assess factors associated with suboptimal diabetes care.
机译:摘要:背景:糖尿病管理项目正在研究在有或没有糖尿病性视网膜病的个体中,最佳糖尿病护理的临床,行为和社会心理障碍。设计:预期队列。参与者:223名无糖尿病视网膜病变和糖尿病视网膜病变的患者。方法:所有个体均接受全面的散瞳检查,人体测量,血液和尿液样本以及社会心理调查问卷。主要结果指标:良好的血糖控制被定义为糖基化血红蛋白<7%,良好的血压控制被定义为收缩压和舒张值≤130和80mmHg,而良好的糖尿病控制被定义为糖基化的血红蛋白<7%和血压值≤130和80mmHg 。结果:检查年龄为26-90岁(平均年龄±标准差= 64.6±11.6)的401位男性(65.4%)和212位女性(34.6%)。所有参与者的糖基化血红蛋白中位数为7.5%(四分位间距= 1.7%)。平均收缩压和舒张压值分别为139.7mmHg(标准差= 18.8)和92.7mmHg(标准差= 30.9)。初步数据分析表明,超过三分之二的糖尿病患者血糖控制较差,与没有糖尿病的糖尿病患者相比,糖尿病视网膜病患者的血糖控制较差(76.3%对49.3%; P <0.001)。对于患有和不患有糖尿病性视网膜病的患者,血压控制相似,总样本中近三分之一(28.5%)的血压控制不良。总体而言,患有糖尿病性视网膜病的患者的糖尿病控制能力较没有糖尿病的患者(24.3%vs. 13.7%; P = 0.002)。结论:我们的发现证实了糖尿病管理项目的实施,该项目旨在评估与糖尿病治疗效果不佳相关的因素。

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