Blood plasma proteins following long-duration space flight

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Blood plasma proteins following long-duration space flight

机译：长时间太空飞行后的血浆蛋白

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Protein composition of blood plasma was an object of investigation in 29 Russian cosmonauts flown on the MIR station from 125 to 366 days. Protein fractions were analyzed using acetate cellulose electrophoresis. Concentration of total protein was determined with the help of the biuret reaction on an automated analyzer. On the second day post flight, mean concentration of total protein and percentage of the protein fractions were equal to baseline values. In the interval between days 7 and 14 post flight, total protein was statistically reduced, alphal- N alpha2-globulins increased and y-globulin reduced, whereas albumin and beta-globulins were unchanged in the average. These results may point to development of an acute reaction in the early period of readaptation to the return from long-duration space flight. environmental medicine

机译：血浆蛋白成分是在MIR站飞行125天至366天的29名俄罗斯宇航员的研究对象。使用乙酸纤维素电泳分析蛋白质级分。借助缩二脲反应在自动分析仪上测定总蛋白浓度。飞行后第二天，总蛋白质的平均浓度和蛋白质级分的百分比等于基线值。在飞行后第7天和第14天之间的间隔中，统计上总蛋白减少，α1-Nα2-球蛋白增加，γ-球蛋白减少，而白蛋白和β-球蛋白的平均值没有变化。这些结果可能表明在重新适应早期从长期太空飞行中返回时出现了急性反应。环境医学

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《Авиаκосмичесκая и эκологичесκая медицина》 |2006年第6期|共4页
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Larina ON;
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正文语种 rus
中图分类放射医学;
关键词
Adaptation; Physiological; Alpha-Globulins; Beta-Globulins; Globins; Space Flight; 适应; 生理学; 甲种球蛋白类; 乙种球蛋白类; 宇宙飞行; 失重;

机译：Adaptation;Physiological;Alpha-Globulins;Beta-Globulins;Globins;Space Flight;适应;生理学;甲种球蛋白类;乙种球蛋白类;宇宙飞行;失重;

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专利

1. Blood plasma proteins following long-duration space flight [J] . Larina ON Авиаκосмичесκая и эκологичесκая медицина . 2006,第6期

机译：长时间太空飞行后的血浆蛋白
2. Latent viral reactivation is associated with changes in plasma antimicrobial protein concentrations during long-duration spaceflight [J] . Spielmann G., Laughlin M. S., Kunz H., Acta astronautica . 2018,第MAY期

机译：潜在的病毒再激活与长期航天过程中血浆抗微生物蛋白浓度的变化有关
3. Oxidative Posttranslational Modifications of Blood Plasma Proteins of Cosmonauts after a Long-Term Flight: Part Ⅱ [J] . I. M. Larina, A. G. Brzhzovsky, A. M. Nosovsky, Human physiology . 2021,第4期

机译：长期飞行后宇航员血浆蛋白血浆蛋白的氧化发生修饰：第Ⅱ部分
4. Development of protein markers for evaluating the blood compatibility of biomaterials: Validation of identified markers by comprehensive multivariate proteomic analysis for plasma proteins adsorbed on the surface of metal materials for stents [C] . Yuki Morishita, Chie Fukui, Toshiyasu Yuba, World biomaterials congress . 2016

机译：开发用于评估生物材料血液相容性的蛋白质标记物：通过对支架金属材料表面吸附的血浆蛋白进行全面的多元蛋白质组分析，对鉴定出的标记物进行验证
5. Radiation transport modeling and assessment to better predict radiation exposure, dose, and toxicological effects to human organs on long-duration space flights. [D] . Denkins, Pamela Sue. 2001

机译：辐射传输建模和评估可以更好地预测长时间太空飞行对人体器官的辐射暴露，剂量和毒理学影响。
6. The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins [O] . Daria N. Kashirina, Andrew J. Percy, Liudmila Kh. Pastushkova, 2019

机译：人体血液蛋白质的定量分析揭示了长时间太空飞行后驱动生理变化的分子机制
7. The molecular mechanisms driving physiological changes after long duration space flights revealed by quantitative analysis of human blood proteins [O] . Daria N. Kashirina, Andrew J. Percy, Liudmila Kh. Pastushkova, 2019

机译：促进在人类血液蛋白的定量分析揭示的长期空间飞行后生理变化的分子机制
8. Identification of Proteins Interacting at Blood or Plasma/Biomaterial Interfaces;Relation to Platelet and White Blood Cell Adhesion,and to Clotting. [R] . vroman,leo solensky, regina p. 1975

机译：鉴定在血液或血浆/生物材料界面相互作用的蛋白质;与血小板和白细胞粘附以及凝血的关系。

Blood plasma proteins following long-duration space flight

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