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首页> 外文期刊>Clinical and experimental ophthalmology >Progression of retinopathy during pregnancy in type 1 diabetes mellitus.
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Progression of retinopathy during pregnancy in type 1 diabetes mellitus.

机译：1型糖尿病妊娠期间视网膜病变的进展。

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PURPOSE: The incidence and risk factors for progression of retinopathy during pregnancy in women with type 1 diabetes mellitus were retrospectively evaluated. METHODS: Fifty-four insulin-dependent diabetic patients at a teaching hospital in Saudi Arabia were followed throughout the pregnancy/puerperium with serial ophthalmic examination. Dilated fundus examination was performed in each trimester and puerperium. RESULTS: Progression of diabetic retinopathy in the study occurred in 13/54 (24%) patients--2/22 (9.1%) patients had no diabetic retinopathy initially, 4/20 (20%) had non-proliferative diabetic retinopathy (NPDR) and 7/12 (58.3%) had proliferative diabetic retinopathy (PDR). Of the eight patients with PDR who had no laser treatment before pregnancy, six (75%) showed progression but only one of the four patients who had PDR and laser treatment prior to pregnancy experienced progression of retinopathy. Eight patients in total received panretinal photocoagulation to arrest the progression of retinal disease during pregnancy and only one of them had laser treatment prior to pregnancy. CONCLUSION: Laser photocoagulation for severe NPDR or early PDR prior to pregnancy may protect against rapid progression of PDR. Visual impairment resulting from progression of PDR can be prevented by aggressive laser treatment during pregnancy. Duration of diabetes>15 years, poor glycaemic control and hypertension are high-risk factors in the progression of diabetic retinopathy in pregnancy.
机译：目的：回顾性评估1型糖尿病妇女妊娠期视网膜病变的发生率和危险因素。方法：在沙特阿拉伯一家教学医院的54名胰岛素依赖型糖尿病患者在整个妊娠/产褥期进行了连续的眼科检查。在每个孕期和产褥期进行眼底检查。结果：本研究中糖尿病性视网膜病变的进展发生在13/54（24％）患者中-2/22（9.1％）患者最初没有糖尿病性视网膜病变，4/20（20％）患有非增生性糖尿病性视网膜病变（NPDR） ）和7/12（58.3％）患有增生性糖尿病视网膜病变（PDR）。在怀孕前未接受激光治疗的8例PDR患者中，有6人（75％）表现为进展，但在怀孕之前接受PDR和激光治疗的4例患者中只有1人发生了视网膜病变。共有八名患者接受了全视网膜光凝术以阻止妊娠期间视网膜疾病的进展，只有一例在妊娠前接受了激光治疗。结论：妊娠前严重NPDR或早期PDR的激光光凝可预防PDR的快速发展。在妊娠期间可以通过积极的激光治疗来预防由PDR进展引起的视力障碍。糖尿病持续时间> 15年，血糖控制不佳和高血压是妊娠糖尿病性视网膜病变进展的高危因素。

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