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A practical pressure measuring method for the upper urinary tract during ureteroscopy

机译:实用的输尿管镜检查中上尿路压力测量方法

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Purpose: The purpose of this study was to develop and test a method for measuring pressure in the upper urinary tract during ureteroscopic operations and to evaluate its effcacy and clinical significance. Methods: A total of 44 patients, each with a ureteral calculus in the proximal ureteral segment, were enrolled in the study group: 21 patients with an acute and 23 with a chronic obstruction. The ureteroscope was passed forward to the upper segment of the obstructed ureter immediately after the calculus was broken and the intraluminal ureteral pressure was then transmitted along with the irrigant flow (0.9% sodium chloride). Results: The mean ureteral pressures of the acute obstruction subgroup, the chronic obstruction subgroup and the control group were 74.5 mmHg (22-180 mmHg), 32.5 mmHg (9-53 mmHg) and 10.2 mmHg (8-13 mmHg), respectively. A significant correlation was found between ureteral pressure and the following indexes: The duration of the obstruction (r=0.985), the diameter of the ureter above the calculus (r=0.878) and the depth of the hydronephrosis of the renal pelvis (r=0.862). No associations were observed between the pressure and the serum creatinine level (r=0.214) or the urinary leukocyte count (r=0.047). The intraluminal pressure correlated with the glomerular flow rate (GFR) of the affected kidney (r =0.975, P =0.001). Conclusions: This new method is non-invasive, practical and reproducible. Measuring the intraluminal pressure of the ureter can provide a valuable index to quantify the severity of the obstruction of the upper urinary tract, which is helpful for the prediction of the affected renal function prognosis.
机译:目的:本研究的目的是开发和测试一种在输尿管镜手术期间测量上尿路压力的方法,并评估其疗效和临床意义。方法:研究组共入选44例患者,每例均在输尿管近端段有输尿管结石,其中21例为急性患者,23例为慢性阻塞。结石破裂后,立即将输尿管镜向前移至阻塞的输尿管上段,然后将腔内输尿管内压力与冲洗液(0.9%氯化钠)一起传输。结果:急性阻塞组,慢性阻塞组和对照组的平均输尿管压力分别为74.5 mmHg(22-180 mmHg),32.5 mmHg(9-53 mmHg)和10.2 mmHg(8-13 mmHg)。发现输尿管压力与以下指标之间存在显着相关性:梗阻持续时间(r = 0.985),结石上方输尿管直径(r = 0.878)和肾盂肾盂积水深度(r = 0.862)。在压力和血清肌酐水平(r = 0.214)或尿白细胞计数(r = 0.047)之间未发现关联。管腔内压力与受累肾脏的肾小球流速(GFR)相关(r = 0.975,P = 0.001)。结论:这种新方法是非侵入性的,实用的且可重复的。测量输尿管腔内压力可以提供有价值的指标,以量化上尿路梗阻的严重程度,这有助于预测受影响的肾功能预后。

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