...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>麻酔 >Pre-treatment with ketamine reduces incidence and severity of pain on propofol injection
【24h】

Pre-treatment with ketamine reduces incidence and severity of pain on propofol injection

机译：氯胺酮预处理可降低丙泊酚注射时的疼痛发生率和严重程度

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The purpose of this study was to evaluate the effect of pre-treatment with ketamine on the reduction of pain during injection of propofol in adult patients. We conducted a prospective, randomized, double-blinded trial. Forty-three patients were randomly allocated to one of two groups according to the agents administered before hand; Group C, normal saline 2 ml and Group K, 1% ketamine 2 ml. The pain on injection was rated as none, mild, moderate, or severe. Sixty-eight percent of patients in the C group experienced pain, while 33% of patients experienced pain in the K group. Thirty-six percent of patients in the C group complained moderate to severe pain but only 9% of patients in the K group. The mechanisms of prevention by ketamine of the pain on propofol-injection could not be clarified from our study, but it may be related to central effects of ketamine. In conclusion, ketamine pre-treatment before propofol administration significantly reduces incidence and severity of pain associated with propofolinjection.
机译：这项研究的目的是评估氯胺酮预处理对成人丙泊酚注射过程中疼痛减轻的影响。我们进行了一项前瞻性，随机，双盲试验。根据之前使用的药物，将43例患者随机分配到两组中的一组中。 C组，生理盐水2 ml，K组，1％氯胺酮2 ml。注射时的疼痛被评定为无，轻度，中度或严重。 C组患者中有68％经历过疼痛，而K组患者中有33％经历过疼痛。 C组中有36％的患者主诉中度至重度疼痛，而K组中只有9％的患者主诉中度至重度疼痛。氯胺酮对异丙酚注射液的疼痛预防机制尚不清楚，但可能与氯胺酮的中枢作用有关。总之，在异丙酚给药前进行氯胺酮预处理可显着降低与异丙酚注射相关的疼痛的发生率和严重程度。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号