• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Computer Methods and Programs in Biomedicine: An International Journal Devoted to the Development, Implementation and Exchange of Computing Methodology and Software Systems in Biomedical Research and Medical Practice >A comprehensive cytogenetics tutorial program, encompassing changeable G-band resolutions
【24h】

A comprehensive cytogenetics tutorial program, encompassing changeable G-band resolutions

机译：全面的细胞遗传学教程程序，包含可变的G波段分辨率

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Chromosome analysis is a basic science with medical implication. Karyotyping is a procedure to study an individual's chromosome make-up. It is time consuming to train students and clinical technologists to recognize patterns of G-banded chromosomes because of the dynamic nature of G-band resolutions in different metaphase spreads. High resolution G-bands are desirable because they provide detailed information for structural analysis. However, it is challenging to identify chromosomes at higher resolution levels even for many cytogenetics technologists. In response to the need for training students to identify human chromosomes at variable G-band resolutions, we present in this paper an advanced version of virtual reality (VR)-based interactive karyotyping program capable of manipulating G-band resolutions for human cytogenetics education. The program can generate different metaphase spreads ranging from short and well separate chromosomes at low G-band resolutions to long, curved, and overlapped chromosomes at high G-band resolutions. Other features include a scoring system, helping strategies, and the progress reports. The traditional "cut and paste" karyotyping method for chromosome separation is incorporated in the software. This method is compared with the "simple clicking" method which is based on an edge detection technique for outlining each chromosome. The comprehensive program is suitable for in-depth training of advanced students,
机译：染色体分析是一门具有医学意义的基础科学。核型分析是研究个体染色体组成的程序。由于不同时期中期G波段分辨率的动态性质，训练学生和临床技术人员识别G波段染色体的模式非常耗时。高分辨率G波段是可取的，因为它们为结构分析提供了详细的信息。然而，即使对于许多细胞遗传学技术人员来说，以更高的分辨率水平鉴定染色体也是一项挑战。为了满足培训学生识别可变G波段分辨率的人类染色体的需求，我们在本文中介绍了基于虚拟现实（VR）的交互式核型分型程序的高级版本，该程序能够操纵G波段分辨率用于人类细胞遗传学教育。该程序可以生成不同的中期扩散，范围从低G波段分辨率的短而分离良好的染色体到高G波段分辨率的长，弯曲和重叠的染色体。其他功能包括评分系统，帮助策略和进度报告。该软件中包含了用于染色体分离的传统“剪切和粘贴”核型分析方法。将该方法与基于边缘检测技术的“简单点击”方法进行比较，以概述每个染色体。全面的课程适用于进阶学生的深入培训，

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号