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首页> 外文期刊>Computer Methods and Programs in Biomedicine: An International Journal Devoted to the Development, Implementation and Exchange of Computing Methodology and Software Systems in Biomedical Research and Medical Practice >Elastic image registration for guiding focal laser ablation of prostate cancer: Preliminary results
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Elastic image registration for guiding focal laser ablation of prostate cancer: Preliminary results

机译：弹性图像配准引导前列腺癌的聚焦激光消融：初步结果

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Purpose: To guide ultrasound-driven prostate photodynamic therapy using information from MRI-based treatment planning. Methods: Robust points matching (RPM) and thin plate splines (TPS) are used to solve correspondences and to map optimally positioned landmarks from MR images to transrectal ultrasound (TRUS) images. The algorithm uses a reduced number of anatomical markers that are initialized on the images. Results: Both phantom and patient data were used to evaluate precision and robustness of the method. Mean registration error (±standard deviation) was of 2.18. ±. 0.25. mm and 1.55. ±. 0.31. mm for patient prostate and urethra, respectively. Repeated tests with different markers initialization conditions showed that the quality of registration was neither influenced by the number of markers nor to the human observer. Conclusion: This method allows for satisfyingly accurate and robust non rigid registration of MRI and TRUS and provides practitioners with substantial help in mapping treatment planning from pre-operative MRI to interventional TRUS.
机译：目的：利用基于MRI的治疗计划中的信息来指导超声驱动的前列腺光动力疗法。方法：鲁棒点匹配（RPM）和薄板样条（TPS）用于求解对应关系，并将最佳位置的地标从MR图像映射到经直肠超声（TRUS）图像。该算法使用减少数量的在图像上初始化的解剖标记。结果：幻像和患者数据均用于评估该方法的准确性和鲁棒性。平均配准误差（±标准偏差）为2.18。 ±。 0.25。毫米和1.55。 ±。 0.31。分别用于病人的前列腺和尿道。用不同标记初始化条件进行的重复测试表明，注册质量既不受标记数量的影响，也不受人类观察者的影响。结论：该方法可以使MRI和TRUS获得令人满意的准确和鲁棒的非刚性配准，并为从术前MRI到介入性TRUS的治疗计划制定工作提供实质性帮助。

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