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首页> 外文期刊>Computer Methods and Programs in Biomedicine: An International Journal Devoted to the Development, Implementation and Exchange of Computing Methodology and Software Systems in Biomedical Research and Medical Practice >Ca analysis: An excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis
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Ca analysis: An excel based program for the analysis of intracellular calcium transients including multiple, simultaneous regression analysis

机译：Ca分析：基于Excel的程序，用于分析细胞内钙瞬变，包括多个同时回归分析

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摘要

Here I present an Excel based program for the analysis of intracellular Ca transients recorded using fluorescent indicators. The program can perform all the necessary steps which convert recorded raw voltage changes into meaningful physiological information. The program performs two fundamental processes. (1) It can prepare the raw signal by several methods. (2) It can then be used to analyze the prepared data to provide information such as absolute intracellular Ca levels. Also, the rates of change of Ca can be measured using multiple, simultaneous regression analysis. I demonstrate that this program performs equally well as commercially available software, but has numerous advantages, namely creating a simplified, self-contained analysis workflow.
机译：在这里，我介绍了一个基于Excel的程序，用于分析使用荧光指示剂记录的细胞内Ca瞬变。该程序可以执行将记录的原始电压变化转换为有意义的生理信息的所有必要步骤。该程序执行两个基本过程。 （1）它可以通过几种方法准备原始信号。 （2）然后可以将其用于分析准备的数据，以提供诸如绝对细胞内钙水平的信息。同样，可以使用多个同时回归分析来测量Ca的变化率。我演示了该程序的性能与市售软件相同，但是具有许多优势，即创建了一个简化的，独立的分析工作流程。

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