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Airway eosinophilia in occupational asthma.

机译:职业性哮喘中的气道嗜酸性粒细胞增多。

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Standardized non-invasive methods for assessing airway inflammation are increasingly used in the investigation of inflammatory respiratory diseases. Monitoring airway inflammation by the analysis of cells in induced sputum or by the fraction of nitric oxide in exhaled air (FeNO) has been proposed in the diagnosis and the management of asthma. Eosinophilic inflammation was detected in approximately 75% of asthmatics in a study not biased by corticosteroid treatment [1], The presence of sputum eosinophilia, or its surrogate elevated FeNO, predicts a better response to corticosteroids compared with sputum neutrophilia [2, 3].
机译:用于评估气道炎症的标准化非侵入性方法越来越多地用于研究炎症性呼吸道疾病。已经提出了通过分析诱导痰中的细胞或通过呼出气中一氧化氮的含量来监测气道炎症的方法,以用于哮喘的诊断和治疗。在一项不受皮质类固醇治疗偏倚的研究中,约有75%的哮喘患者检测到嗜酸性粒细胞炎症[1]。痰中嗜酸性粒细胞增多或其替代FeNO升高,提示对皮质类固醇的反应优于嗜中性粒细胞痰[2,3]。

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