• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical and experimental allergy : >Caesarean sections and risk of wheezing in childhood and adolescence: data from two birth cohort studies in Brazil.
【24h】

Caesarean sections and risk of wheezing in childhood and adolescence: data from two birth cohort studies in Brazil.

机译：剖腹产和儿童期和青春期的喘息风险：来自巴西两项出生队列研究的数据。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: There is evidence from two meta-analyses that children born through caesarean section (C-section) may have an increased risk of developing asthma compared with those born through vaginal delivery. Objective To evaluate the association between mode of delivery and wheezing (current and persistent) in childhood and adolescence, in two birth cohort studies in Brazil. METHODS: The outcome variable was based on the International Study of Allergy and Asthma questionnaire, which collects information about wheezing within the 12 months before the interview. Persistent wheezing was defined when it was present in more than one follow-up at different ages, in the 1993 cohort. The questions were asked to mothers when children were aged 4 years (1993 and 2004 cohorts) and directly to cohort participants at 11 and 15 years (1993 cohort). Mode of delivery was collected by the research team of each cohort when children were born. RESULTS: Response rates in the last follow-up visit of the 1993 and 2004 cohorts were 85% and 92%, respectively. The prevalence of current wheezing increased from 20% to 28% at 4 years from 1993 to 2004; at 11 and 15 years, the prevalence was around 14% and 12%, in the 1993 cohort. The proportion of C-sections increased from 30.5% to 45% between 1993 and 2004. In each cohort, the prevalence of current wheezing was similar among children born through vaginal and C-section. The risk for persistent wheezing in the 1993 cohort was higher among girls born through C-section than boys. CONCLUSION: Despite the increase in the proportion of C-section in two cohorts in Southern Brazil, we found no evidence of an association between mode of delivery and the subsequent risk of wheezing. Among girls, although there was no statistical significance, the risk was higher for those born by C-section, especially regarding persistent wheezing.
机译：背景：从两项荟萃分析中有证据表明，与通过阴道分娩出生的孩子相比，通过剖腹产出生的孩子患哮喘的风险可能更高。目的在巴西的两项出生队列研究中，评估分娩方式与儿童和青春期喘息（当前和持续）之间的关联。方法：结果变量基于过敏和哮喘国际调查表，该调查表在访谈前的12个月内收集了有关喘息的信息。持续性喘息的定义是在1993年的队列中，在不同年龄的一次以上随访中发现了持续性喘息。当孩子年龄为4岁时（1993年和2004年队列），问题被问给母亲，而在11岁和15岁时（1993年队列），问题直接问给参与者。分娩方式由每个队列的研究团队在孩子出生时收集。结果：在1993年和2004年队列的最后一次随访中，回应率分别为85％和92％。从1993年到2004年的4年间，当前的喘息流行率从20％增加到28％;在1993年队列中，在11岁和15岁时，患病率分别约为14％和12％。在1993年至2004年之间，剖腹产的比例从30.5％增加到45％。在每个队列中，通过阴道和剖腹产出生的孩子中当前的喘息流行率相似。通过剖腹产出生的女孩在1993年队列中持续喘息的风险高于男孩。结论：尽管巴西南部两个队列中剖腹产的比例有所增加，但我们并未发现分娩方式与随后发生喘息风险之间存在关联的证据。在女孩中，尽管没有统计学意义，但剖腹产的风险更高，尤其是持续性喘息。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号