首页> 外文期刊>Clinical and experimental allergy : >Exhaled nitric oxide in childhood asthma: a review.
【24h】

Exhaled nitric oxide in childhood asthma: a review.

机译:儿童哮喘中呼出气一氧化氮的研究进展。

获取原文
获取原文并翻译 | 示例
           

摘要

As an 'inflammometer', the fraction of nitric oxide in exhaled air (Fe(NO)) is increasingly used in the management of paediatric asthma. Fe(NO) provides us with valuable, additional information regarding the nature of underlying airway inflammation, and complements lung function testing and measurement of airway hyper-reactivity. This review focuses on clinical applications of Fe(NO) in paediatric asthma. First, Fe(NO) provides us with a practical tool to aid in the diagnosis of asthma and distinguish patients who will benefit from inhaled corticosteroids from those who will not. Second, Fe(NO) is helpful in predicting exacerbations, and predicting successful steroid reduction or withdrawal. In atopic asthmatic children Fe(NO) is beneficial in adjusting steroid doses, discerning those patients who require additional therapy from those whose medication dose could feasibly be reduced. In pre-school children Fe(NO) may be of help in the differential diagnosis of respiratory symptoms, and may potentially allow for better targeting and monitoring of anti-inflammatory treatment.
机译:作为“炎症计”,呼出空气中的一氧化氮(Fe(NO))分数越来越多地用于控制小儿哮喘。 Fe(NO)为我们提供了有关潜在气道炎症性质的有价值的其他信息,并补充了肺功能测试和气道高反应性的测量。这篇综述着重于Fe(NO)在小儿哮喘中的临床应用。首先,Fe(NO)为我们提供了一种实用的工具,可帮助诊断哮喘,并从吸入性糖皮质激素获益的患者和未吸入糖皮质激素的患者中区分出来。其次,Fe(NO)有助于预测病情恶化,并预测类固醇的成功减少或戒断。在特应性哮喘儿童中,Fe(NO)有助于调整类固醇剂量,从而可以从可能降低药物剂量的患者中识别出需要额外治疗的患者。在学龄前儿童中,Fe(NO)可能有助于呼吸道症状的鉴别诊断,并可能潜在地更好地针对和监测抗炎治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号