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Increasing prevalence of atopic eczema in Taiwanese adolescents from 1995 to 2001.

机译:从1995年到2001年,台湾青少年特应性湿疹的患病率上升。

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BACKGROUND: The prevalence of atopic eczema in adolescents has recently been reported as increasing in many countries, a phenomenon yet to be fully explained. This study compared the prevalence of atopic eczema among Taiwanese adolescents with individual-level risk factors and community-level data of temperature, relative humidity, and air pollutants to determine whether changes in these factors could explain the observed change in prevalence. METHODS: We conducted two nationwide, cross-sectional surveys of atopic illness and symptoms among Taiwanese 12-15-year-old schoolchildren in 1995-1996 and 2001. The effects of personal and environmental factors were assessed and temporal changes of outdoor monitoring data were also compared with the prevalence difference of atopic eczema. RESULTS: A total of 42 919 adolescents from the 1995 to 1996 survey and 10 215 adolescents from the 2001 survey attended schools located within 1 km of 22 monitoring stations. The 12-month prevalence of atopic eczema increased significantly during this period [adjusted prevalence ratio (PR)=1.43, 95% confidence interval (CI) 1.21-1.70 in boys; PR=1.77, 95% CI 1.49-2.10 in girls]. After adjustment for potential risk factors, the prevalence differences were statistically unchanged. Although parental education level contributed the most, changes in personal and environmental factors might not explain the observed prevalence increases of atopic eczema. Temporal change in the relative humidity was significantly associated with prevalence increase among boys but its contribution was also small. CONCLUSION: Correlates of the investigated risk factors that have changed over time still underlie the prevalence increases of atopic eczema in Taiwanese adolescents. The exact reasons for the rising trends remain to be elucidated.
机译:背景:最近,在许多国家,青少年特应性湿疹的发病率呈上升趋势,这一现象有待充分解释。这项研究将台湾青少年的特应性湿疹患病率与个人风险因素以及社区层面的温度,相对湿度和空气污染物数据进行了比较,以确定这些因素的变化是否可以解释观察到的患病率变化。方法:我们在1995-1996年和2001年对台湾12-15岁小学生的特应性疾病和症状进行了两项全国性横断面调查。评估了个人和环境因素的影响,并评估了户外监测数据的时间变化。还与特应性湿疹的患病率进行了比较。结果:从1995年到1996年的调查中,共有42 919名青少年和2001年调查的10 215名青少年在22个监测站附近1公里内的学校就读。在此期间,特应性湿疹的12个月患病率显着增加[男孩的调整患病率(PR)= 1.43,95%置信区间(CI)为1.21-1.70; PR = 1.77,女童95%CI 1.49-2.10]。在对潜在危险因素进行调整后,患病率差异在统计学上没有变化。尽管父母的教育程度贡献最大,但个人和环境因素的变化可能无法解释观察到的特应性湿疹患病率增加。相对湿度的时间变化与男孩患病率增加显着相关,但其贡献也很小。结论:台湾青少年的特应性湿疹患病率增加仍是所调查的危险因素随时间变化的相关性。上升趋势的确切原因尚待阐明。

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