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Action plans for the long-term management of anaphylaxis: systematic review of effectiveness.

机译：过敏反应的长期管理行动计划：有效性的系统评价。

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Background Anaphylaxis is a severe, potentially life-threatening allergic reaction. Most reactions occur in the absence of a healthcare professional and there is a considerable risk of recurrence in those with a past history of anaphylaxis. The concept of action plans has been developed to facilitate long-term self-management of chronic disorders with a view to promoting patient empowerment and improving health outcomes. Although increasingly advocated for use in anaphylaxis, the effectiveness of this approach in this context is unknown. Objectives To assess the effectiveness of action plans as part of the long-term self-management of anaphylaxis in improving health outcomes. Methods Standard systematic review techniques were used. We searched CENTRAL, Cochrane, Medline and Embase databases, contacted an international panel of anaphylaxis experts and relevant pharmaceutical companies and searched key web-based databases of trials (http://www.clinicaltrials.gov, http://www.controlledtrials.com and http://www.nrr.nhs.uk) for published, unpublished and on-going randomized or quasi-randomized controlled trials of action plans in anaphylaxis management. There was no restriction used with respect to the language of publication. Searches were completed in summer 2006. Results None of the 1026 potentially relevant studies identified fulfilled the inclusion criteria for this review. Conclusions Although there are potential major benefits of routinely issuing anaphylaxis action plans, there is currently no robust evidence to guide clinical practice. Pragmatic randomized-controlled trials of anaphylaxis action plans are urgently needed; in the meantime, national and international guidelines should make clear this major gap in the evidence base.
机译：背景过敏反应是一种严重的，可能威胁生命的过敏反应。大多数反应是在没有医疗保健专业人员的情况下发生的，过去有过敏反应史的患者存在很大的复发风险。已经制定了行动计划的概念，以促进慢性疾病的长期自我管理，以促进赋予患者权力并改善健康结果。尽管越来越多地主张将其用于过敏反应，但这种方法在这种情况下的有效性尚不清楚。目的评估作为长期自我管理过敏反应以改善健康结果的一部分的行动计划的有效性。方法采用标准的系统评价技术。我们搜索了CENTRAL，Cochrane，Medline和Embase数据库，并联系了过敏反应专家和相关制药公司的国际小组，并搜索了基于网络的主要试验数据库（http：//www.clinicaltrials.gov，http：//www.controltrials。 com和http://www.nrr.nhs.uk）进行过敏反应管理中行动计划的已发布，未发布和正在进行的随机或半随机对照试验。对于发布语言没有任何限制。搜索工作于2006年夏季完成。结果确定的1026项潜在相关研究中，没有一项符合本评价的纳入标准。结论尽管常规发布过敏反应行动计划可能具有潜在的主要好处，但目前尚无强有力的证据指导临床实践。急需对过敏反应行动计划进行实用的随机对照试验。同时，国家和国际准则应明确证据基础上的这一主要差距。

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