Enhanced allergic airway disease in old mice is associated with a Th17 response.

C Brandenberger; N Li; D N Jackson-Humbles; C E Rockwell; J G Wagner; J R Harkema

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Enhanced allergic airway disease in old mice is associated with a Th17 response.

机译：老年小鼠过敏性气道疾病增强与Th17反应有关。

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Our findings in mice suggest that the severity and character of allergic airway disease are age dependent, with a bias towards a Th17 immune response with aging. Elderly, asthmatics may be prone to develop severe allergic airway inflammation with a mixed Th2/Th17 immune response.

机译：我们在小鼠中的发现表明，过敏性气道疾病的严重程度和特征与年龄有关，并且随着年龄的增长而倾向于Th17免疫反应。老年人，哮喘患者可能容易出现严重的过敏性气道炎症，并伴有Th2 / Th17混合免疫反应。

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《Clinical and experimental allergy :》 |2014年第10期|共11页
作者
C Brandenberger; N Li; D N Jackson-Humbles; C E Rockwell; J G Wagner; J R Harkema;
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正文语种 eng
中图分类医学免疫学;
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1. Enhanced allergic airway disease in old mice is associated with a Th17 response. [J] . C Brandenberger, N Li, D N Jackson-Humbles, Clinical and experimental allergy : . 2014,第10期

机译：老年小鼠过敏性气道疾病增强与Th17反应有关。
2. Livestock farm particulate matter enhances airway inflammation in mice with or without allergic airway disease [J] . Dingyu Liu, James G. Wagner, Jack R. Harkema, World Allergy Organization Journal . 2020,第4期

机译：牲畜农场颗粒物质增强了小鼠的气道炎症，或没有过敏气道疾病
3. Expansion of commensal fungus Wallemia mellicola in the gastrointestinal mycobiota enhances the severity of allergic airway disease in mice [J] . Joseph H. Skalski, Jose J. Limon, Purnima Sharma, PLoS Pathogens . 2018,第9期

机译：扩张的非团结菌在胃肠霉菌菌菌菌菌菌菌菌菌菌菌菌，增强了小鼠过敏气道病的严重程度
4. Effects of Asian Sand Dust on Allergic Airway Inflammation in Mice [C] . Takamichi Ichinose, Miao HE, Seiichi Yoshida, Conference on Environmental Pollution and Public Health . 2012

机译：亚洲沙尘对小鼠过敏性气道炎症的影响
5. Soft x-ray enhanced electrostatic precipitation of biological aerosols: Attenuation of microbial respiratory infections and allergic airway disease in murine models. [D] . Kettleson, Eric Matthew. 2011

机译：软X射线增强了生物气溶胶的静电沉淀：鼠模型中微生物呼吸道感染和过敏性气道疾病的减轻。
6. Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease [O] . Sidra M. Hoffman, Jane E. Tully, Karolyn G. Lahue, -1

机译：glutaredoxin-1的基因消融导致过敏性气道疾病小鼠气道高反应性和粘液化生的增强分辨率
7. Livestock farm particulate matter enhances airway inflammation in mice with or without allergic airway disease [O] . Dingyu Liu, James G. Wagner, Jack R. Harkema, 2020

机译：牲畜农场颗粒物质增强了小鼠的气道炎症，或没有过敏气道疾病

Enhanced allergic airway disease in old mice is associated with a Th17 response.

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