Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months

El-Heis S.; Crozier S. R.; Robinson S. M.; Harvey N. C.; Cooper C.; Inskip H. M.; Godfrey K. M.

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Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months

机译：孕晚期孕妇较高的烟酰胺和相关代谢产物血清浓度与12个月大的后代异位性湿疹风险较低相关

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Background Evidence that atopic eczema partly originates in utero is increasing, with some studies linking the risk of developing the condition with aspects of maternal diet during pregnancy. Nicotinamide, a naturally occurring nutrient that is maintained through the dietary intakes of vitamin B3 and tryptophan, has been used in the treatment of some skin conditions including atopic eczema. Objective To examine the relation of maternal serum concentrations of nicotinamide and related tryptophan metabolites to the risk of atopic eczema in the offspring.

机译：背景异位性湿疹部分起源于子宫的证据正在增加，一些研究将这种疾病的风险与怀孕期间孕妇饮食的某些方面联系起来。烟酰胺是一种天然存在的营养物质，可通过饮食中摄取维生素B3和色氨酸来维持，已被用于治疗某些皮肤疾病，包括特应性湿疹。目的探讨母亲血清烟酰胺和相关色氨酸代谢产物的浓度与后代异位性湿疹风险的关系。

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《Clinical and experimental allergy :》 |2016年第10期|共7页
作者
El-Heis S.; Crozier S. R.; Robinson S. M.; Harvey N. C.; Cooper C.; Inskip H. M.; Godfrey K. M.;
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正文语种 eng
中图分类医学免疫学;
关键词
atopic eczema; maternal micronutrients; nicotinamide;

机译：特应性湿疹;母亲微量营养素;烟酰胺;

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1. Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months [J] . El-Heis S., Crozier S. R., Robinson S. M., Clinical and experimental allergy : . 2016,第10期

机译：孕晚期孕妇较高的烟酰胺和相关代谢产物血清浓度与12个月大的后代异位性湿疹风险较低相关
2. Maternal dietary patterns during pregnancy and risk of wheeze and eczema in Japanese infants aged 16-24 months: the Osaka Maternal and Child Health Study. [J] . Miyake Y, Okubo H, Sasaki S, Pediatric allergy and immunology: official publication of the European Society of Pediatric Allergy and Immunology . 2011,第7期

机译：《大阪市母婴健康研究》，孕期孕妇的饮食习惯以及16-24个月大的日本婴儿的喘息和湿疹风险。
3. Maternal fat consumption during pregnancy and risk of wheeze and eczema in Japanese infants aged 16-24 months: the Osaka Maternal and Child Health Study. [J] . Miyake Y, Sasaki S, Tanaka K Thorax: The Journal of the British Thoracic Society . 2009,第9期

机译：《大阪市母婴健康研究》，孕期孕妇的脂肪消耗以及16-24个月大的日本婴儿的喘息和湿疹风险。
4. DDE and PCS serum concentration in maternal blood and their adult female offspring [C] . Wilfried Karmaus, Wei-Wen Hsu, Janet Rose Osuch, Annual conference of the International Society of Exposure Science . 2014

机译：母血及其成年雌性后代中的DDE和PCS血清浓度
5. Risk factors for maternal low weight gain during pregnancy and associations with offspring body size and fat distribution. [D] . Wilcox, Sarah K. 2006

机译：孕期孕产妇体重增加低的危险因素，以及与后代体重和脂肪分布有关。
6. Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months [O] . S El-Heis, SR Crozier, SM Robinson, -1

机译：孕晚期孕妇较高的烟酰胺和相关代谢产物血清浓度与12个月大时后代异位性湿疹风险较低相关
7. Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months. [O] . El-Heis, S, Crozier, SR, Robinson, SM, 2016

机译：孕晚期孕妇较高的烟酰胺和相关代谢产物血清浓度与12个月大时后代异位性湿疹风险较低相关。

Higher maternal serum concentrations of nicotinamide and related metabolites in late pregnancy are associated with a lower risk of offspring atopic eczema at age 12 months

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