• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Clinical and experimental allergy : >Clinical value of negative skin tests to iodinated contrast media.
【24h】

Clinical value of negative skin tests to iodinated contrast media.

机译：含碘造影剂皮肤试验阴性的临床价值。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Several studies have shown that skin tests are useful tools for the diagnosis of iodinated contrast medium (ICM) allergy, but the real number of false negative results is not known. OBJECTIVE: To evaluate the negative predictive value of ICM skin tests. MATERIAL AND METHODS: One hundred and fifty-nine patients tested in our department because of a previous ICM reaction over the last 9 years were called and asked standardized questions about ICM re-exposure. RESULTS: Twenty-nine patients had been re-exposed to ICM. There were 20 (69.0%) females and the median age was 55 (34-60) years. The median time interval between the reaction and skin testing was 11.9 (1.6-21.5) years. Twenty-four patients (82%) had an immediate reaction, four a non-immediate (13.8%) reaction and no data were available for one patient. Two patients had positive ICM skin tests previously and were re-exposed to a negatively skin-tested ICM and did not react. Only two patients presented a mild reaction during ICM re-injection: one immediate (generalized urticaria lasting for 3 days) and one non-immediate maculopapular reaction. The patient with urticaria was re-tested and re-challenged (negative). The other patient was unable to return for re-testing. CONCLUSION: Skin testing for ICM hypersensitivity has a negative predictive value of 96.6% (95% CI: 89.9-103.2) and none of the reactions in skin-test-negative patients were severe. Multi-centric large surveys are still needed for confirmation.
机译：背景：多项研究表明，皮肤测试是诊断碘化造影剂（ICM）过敏的有用工具，但假阴性结果的真实数目尚不清楚。目的：评估ICM皮肤测试的阴性预测价值。材料和方法：召集了因过去9年中ICM先前反应而在我科接受检查的159名患者，并询问了有关ICM再暴露的标准化问题。结果：29名患者被重新暴露于ICM。有20位女性（69.0％），中位年龄为55岁（34-60）。反应和皮肤测试之间的中位时间间隔为11.9（1.6-21.5）年。 24例患者（82％）有即时反应，4例非立即反应（13.8％），并且无数据可用于一名患者。两名患者先前的ICM皮肤测试阳性，然后再次暴露于皮肤测试的ICM阴性，并且没有反应。仅2例患者在ICM重新注射期间出现轻度反应：1例即刻（持续性荨麻疹持续3天）和1例非立即性斑丘疹反应。荨麻疹患者接受了重新测试并再次受到挑战（阴性）。另一位患者无法返回进行重新测试。结论：皮肤测试对ICM超敏反应的阴性预测值为96.6％（95％CI：89.9-103.2），皮肤测试阴性患者的反应均不严重。仍需要多中心大型调查来进行确认。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号