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Epidemiology of anaphylaxis

机译：过敏反应的流行病学

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Knowledge about the epidemiology of anaphylaxis is based on data from various sources: clinical practice, large secondary clinical and administrative databases of primary care or hospitalized patients, and recent surveys with representative samples of the general population. As several similar results are often reported in several publications and populations, such findings are highly like to be robust. One such finding is that the incidence and prevalence of anaphylaxis are higher than previously thought. Publications from the last 5years reveal an incidence of between 50 and 112 episodes per 100000 person-years; estimated prevalence is 0.3-5.1% depending on the rigour of the definitions used. Figures are higher in children, especially those aged 0-4years. Publications from various geographical areas based on clinical and administrative data on hospitalized patients suggest that the frequency of admissions due to anaphylaxis has increased (5-7-fold in the last 10-15years). Other publications point to a geographic gradient in the incidence of anaphylaxis, with higher frequencies recorded in areas with few hours of sunlight. However, these trends could be the result of factors other than a real change in the incidence of anaphylaxis, such as changes in disease coding and in the care provided. Based on data from the records of voluntary declarations of death by physicians and from large national databases, death from anaphylaxis remains very infrequent and stands at 0.35-1.06 deaths per million people per year, with no increases observed in the last 10-15years. Although anaphylaxis can be fatal, recurrence of anaphylaxis - especially that associated with atopic diseases and hymenoptera stings - affects 26.5-54% of patients.
机译：关于过敏反应流行病学的知识是基于来自各种来源的数据：临床实践，大型的二级医疗或住院患者的二级临床和行政数据库，以及最近对普通人群的代表性样本进行的调查。由于在一些出版物和人群中经常报告几种类似的结果，因此，这种发现非常有力。这样的发现之一是过敏反应的发生率和患病率比以前认为的要高。最近5年的出版物显示每100000人年发生50到112集。根据所用定义的严格程度，估计的患病率是0.3-5.1％。儿童的数字更高，尤其是0-4岁的儿童。根据住院患者的临床和行政数据，来自各个地区的出版物表明因过敏反应而入院的频率有所增加（在过去10-15年中增加了5-7倍）。其他出版物指出过敏反应的发生率存在地域梯度，在几小时的日照区域记录到的频率更高。但是，这些趋势可能是由于过敏反应发生率的实际变化以外的因素所致，例如疾病编码和所提供护理的变化。根据医生自愿宣布死亡的记录以及国家大型数据库的数据，因过敏反应而死亡的人数仍然很少，每年每百万人中有0.35-1.06例死亡，在最近的10-15年中未见增加。尽管过敏反应可能是致命的，但过敏反应的复发（尤其是与特应性疾病和膜翅目刺伤相关的复发）影响26.5-54％的患者。

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