Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells

Qamar N.; Fishbein A. B.; Erickson K. A.; Cai M.; Szychlinski C.; Bryce P. J.; Schleimer R. P.; Fuleihan R. L.; Singh A. M.

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Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells

机译：先前过敏儿童对食物的天然耐受性获得特征是抗原特异性并与调节性T细胞亚群的增加有关

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BackgroundFood allergy affects approximately 6-8% of children, and increasing in prevalence. Some children naturally outgrow their food allergy without intervention, but the mechanisms by which this occurs remain poorly understood. We sought to investigate the role of regulatory T cells in the development of naturally acquired tolerance.

机译：背景食品过敏影响大约6-8％的儿童，并且患病率正在增加。一些孩子自然会在没有干预的情况下超过食物过敏，但这种情况发生的机理仍知之甚少。我们试图研究调节性T细胞在自然获得的耐受性发展中的作用。

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《Clinical and experimental allergy :》 |2015年第11期|共10页
作者
Qamar N.; Fishbein A. B.; Erickson K. A.; Cai M.; Szychlinski C.; Bryce P. J.; Schleimer R. P.; Fuleihan R. L.; Singh A. M.;
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正文语种 eng
中图分类医学免疫学;
关键词
antigen specificity; food allergy; IL-10; natural tolerance; T regulatory cells;

机译：抗原特异性;食物过敏;IL-10;自然耐受性;T调节细胞;

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1. Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells [J] . Qamar N., Fishbein A. B., Erickson K. A., Clinical and experimental allergy : . 2015,第11期

机译：先前过敏儿童对食物的天然耐受性获得特征是抗原特异性并与调节性T细胞亚群的增加有关
2. Antigen specificity is not required for modulation of lung allergic responses by naturally occurring regulatory T cells. [J] . Joetham A, Takeda K, Okamoto M The Journal of Immunology: Official Journal of the American Association of Immunologists . 2009,第3期

机译：通过天然存在的调节性T细胞调节肺部过敏反应不需要抗原特异性。
3. Antigen specificity is not required for modulation of lung allergic responses by naturally occurring regulatory T cells. [J] . Joetham A, Takeda K, Okamoto M The Journal of Immunology: Official Journal of the American Association of Immunologists . 2009,第3期

机译：通过天然存在的调节性T细胞调节肺部过敏反应不需要抗原特异性。
4. Development and function of IL-10-secreting regulatory T cells: Comparison with naturally occurring CD4~+CD25~+ regulatory T cells [C] . Anne OGarra Uehara Memorial Foundation Symposium on the Innate Immune System . 2005

机译：IL-10分泌监管T细胞的开发和功能：与天然存在的CD4〜+ CD25〜+调节性T细胞的比较
5. Peanut Allergic Children Residing in Olmsted County, MN: An Examination of the Prevalence in 2007, Incidence Rates from 1999--2007 and Association between Peanut-Specific IgE Level, Tolerance and Reaction Severity. [D] . Rinaldi, Maria Carol. 2011

机译：居住在明尼苏达州奥尔姆斯特德县的花生过敏儿童：2007年患病率调查，1999--2007年的发病率以及花生特异性IgE水平，耐受性和反应严重性之间的关联。
6. Naturally Occurring Tolerance Acquisition to Foods in Previously Allergic Children is Characterized by Antigen Specificity and Associated with Increased Subsets of Regulatory T cells [O] . Nashmia Qamar, Anna B. Fishbein, Kristin A. Erickson, -1

机译：对以前过敏儿童食品的自然耐受性获得具有抗原特异性并与调节性T细胞亚群相关
7. Antigen Specificity Is not Required for Modulation of Lung Allergic Responses by Naturally Occurring Regulatory T Cells [O] . Anthony Joetham, Katsuyuki Takeda, Masakazu Okamoto, 2009

机译：通过天然存在的调节性T细胞来调节肺过敏响应不需要抗原特异性

Naturally occurring tolerance acquisition to foods in previously allergic children is characterized by antigen specificity and associated with increased subsets of regulatory T cells

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