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Stroop task among patients with obsessive-compulsive disorder (OCD) and pathological gambling (PG) in methadone maintenance treatment (MMT)

机译:美沙酮维持治疗(MMT)中强迫症(OCD)和病理性赌博(PG)患者的Stroop任务

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Objectives. To evaluate the impaired attention selection (Stroop interference effect) and general performance [reaction times (RTs)] on the Stroop task among methadone maintenance treatment (MMT) patients with obsessive compulsive disorder (OCD), pathological gambling (PG), both PG/OCD or none, and the influence if having ADHD. Methods. Eighty-six patients and 15 control subjects underwent the Stroop task, which measured RTs of condition-related words (color, obsessive compulsive disorder, pathological gambling, addiction) and neutral words. Results. MMT patients had longer RTs on the Stroop task compared with controls. RTs were longer among patients with OCD and in those who abused drugs on the study day. The combined PG/OCD group had the longest RTs, but they were also characterized as abusing more drugs, being older, and having worse cognitive status. Stroop color interference differed only among MMT patients with ADHD, and it was higher among those with OCD than those without OCD. The modified condition-related Stroop did not show any interference effect of OCD, addiction, or gambling words. Conclusions. MMT patients had generally poorer performance, as indicated by longer RTs, that were related to clinical OCD, drug abuse, poor cognitive state, and older age. Patients with both clinical OCD and ADHD had a higher Stroop interference effect, which is a reflection of an attention deficit. In order to improve clinical approach and treatment of MMT patients, OCD and ADHD should be evaluated (and treated as needed).
机译:目标。要评估美沙酮维持治疗(MMT)强迫症(OCD),病理性赌博(PG),美沙酮维持治疗(MMT)患者的Stroop任务的注意力选择受损(Stroop干扰效应)和一般表现[反应时间(RTs)]是否有强迫症,以及是否患有多动症。方法。 86位患者和15位对照受试者接受了Stroop任务,该任务测量了与条件相关的单词(颜色,强迫症,病理性赌博,成瘾)和中性单词的RT。结果。与对照组相比,MMT患者在Stroop任务上的RT更长。在研究之日,强迫症患者和滥用药物者的RTs更长。 PG / OCD组合治疗组的RTs最长,但它们的特征还在于滥用更多药物,年龄更大且认知状态较差。 Stroop颜色干扰仅在患有ADHD的MMT患者中有所不同,患有OCD的患者比没有OCD的患者更高。修改后的与条件有关的Stroop没有显示强迫症,成瘾或赌博字词的任何干扰作用。结论如较长的RTs所示,MMT患者通常表现较差,这与临床强迫症,药物滥用,不良的认知状态和年龄较大有关。具有临床强迫症和注意力缺陷多动障碍的患者均具有较高的Stroop干扰作用,这是注意力不足的反映。为了改善MMT患者的临床方法和治疗,应评估OCD和ADHD(并根据需要进行治疗)。

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