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Allergic contact dermatitis caused by isocyanates in resin jewellery

机译:树脂珠宝中的异氰酸酯引起的过敏性接触性皮炎

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摘要

A 3 5-year-old female office worker attended a popular weekend course to develop her interest in making resin jewellery. This involved using a two-part polyurethane resin system that, according to the Material Safety Data Sheet (MSDS), contained 70-90% 4,4'-dicyclohexylmethane-4,4'-diisocyanate (DMDI; CAS 5124-30-1). The two components were mixed, poured into a silicone mould, and allowed to set. On one occasion when the patient did not use gloves, her skin came into direct contact with the polyurethane mixture. The next day, she developed an acute pruritic eruption on her right index finger. Two weeks later, after further resin jewellery making, she developed a pruritic eczematous eruption on her face, neck, and hands. This resolved with topical and oral corticosteroids and avoidance of further jewellery making. There were no associated respiratory symptoms. She no longer undertakes any jewellery making, and has had no recurrences.
机译:3名5岁的女性上班族参加了一个受欢迎的周末课程,以提高她对制作树脂珠宝的兴趣。这涉及使用由两部分组成的聚氨酯树脂体系,根据材料安全数据表(MSDS),该体系包含70-90%4,4'-二环己基甲烷-4,4'-二异氰酸酯(DMDI; CAS 5124-30-1 )。将两种成分混合,倒入硅树脂模具中,并使其固化。在一种情况下,当病人不戴手套时,她的皮肤直接与聚氨酯混合物接触。第二天,她的右手食指出现急性瘙痒疹。两周后,在进一步制作树脂珠宝之后,她的脸,脖子和手上出现了瘙痒性湿疹发作。通过局部和口服皮质类固醇解决了这一问题,避免了进一步的珠宝制作。没有相关的呼吸道症状。她不再从事任何珠宝首饰制作,并且没有重复活动。

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