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首页> 外文期刊>Contact dermatitis >Current patch test results with the European baseline series and extensions to it from the 'European Surveillance System on Contact Allergy' network, 2007-2008
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Current patch test results with the European baseline series and extensions to it from the 'European Surveillance System on Contact Allergy' network, 2007-2008

机译:2007-2008年“接触过敏欧洲监测系统”网络上最新的欧洲基准系列补丁测试结果及其扩展

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Background. The pattern of contact sensitization to the supposedly most important allergens assembled in the baseline series differs between countries, presumably at least partly because of exposure differences. Objectives. To describe the prevalence of contact sensitization to allergens tested in consecutive patients in the years 2007 and 2008, and to discuss possible differences. Methods. Data from the 39 departments in 11 European countries comprising the European Surveillance System on Contact Allergy network () in this period have been pooled and analysed according to common standards. Results. Patch test results with the European baseline series, and country-specific or department-specific additions to it, obtained in 25 181 patients, showed marked international variation. Metals and fragrances are still the most frequent allergens across Europe. Some allergens tested nationally may be useful future additions to the European baseline series, for example methylisothiazolinone, whereas a few long-term components of the European baseline series, namely primin and clioquinol, no longer warrant routine testing. Conclusions. The present analysis points to 'excess' prevalences of specific contact sensitization in some countries, although interpretation must be cautious if only few, and possibly specialized, centres are representing one country. A comparison as presented may help to target in-depth research into possible causes of 'excess' exposure, and/or consideration of methodological issues, including modifications to the baseline series.
机译:背景。各国对基线系列中据称最重要的过敏原的接触敏化方式在各国之间有所不同,大概至少部分是由于接触差异。目标。描述接触致敏在2007年和2008年连续患者中检测到的过敏原的患病率,并讨论可能的差异。方法。已根据共同标准汇总并分析了来自欧洲11个国家/地区的39个部门的数据,其中包括欧洲同期接触过敏网络监测系统()。结果。在25 181名患者中获得的具有欧洲基线系列以及其特定国家或部门特定补充的补丁测试结果显示出明显的国际差异。金属和香料仍然是整个欧洲最常见的过敏原。全国范围内测试的某些过敏原可能是欧洲基准系列将来有用的补充,例如甲基异噻唑啉酮,而欧洲基准系列的一些长期成分,即Primin和Clioquinol,不再需要常规测试。结论目前的分析指出,在某些国家中,特定的接触敏锐度“过高”,尽管只有少数几个,可能是专门的中心代表一个国家,解释必须谨慎。进行的比较可能有助于针对“过度”暴露的可能原因进行深入研究,和/或考虑方法问题,包括对基准系列进行修改。

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