Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.

Moon HI; Kim TI; Cho H

首页> 外文期刊>Bioorganic and Medicinal Chemistry Letters >Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.

【24h】

Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.

机译：鉴定潜在的和选择性的胶原酶，来自Cretaegus pinnatifida的明胶酶抑制剂。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Four oligomeric procyanidins were isolated from the MeOH extracts of the leaves of Crataegus pinnatifida (Rosaceae). Investigation of collagenase and gelatinase inhibitory natural components afforded four oligomeric procyanidins. Of these, 2 and 3 exhibited collagenase inhibitory activity (IC(50)) at a concentration of less than 1 microM, and 3 showed gelatinases A and B inhibitory activity (IC(50)) at 0.4 and 2.3 microM, respectively.

机译：从山楂（Cretaegus pinnatifida）（蔷薇科）的MeOH提取物中分离出四种低聚原花青素。对胶原酶和明胶酶抑制性天然成分的研究提供了四个寡聚原花青素。其中，2和3在小于1 microM的浓度下显示胶原酶抑制活性（IC（50）），3在0.4和2.3 microM的浓度下显示明胶酶A和B抑制活性（IC（50））。

著录项

来源
《Bioorganic and Medicinal Chemistry Letters》 |2010年第3期|共3页
作者
Moon HI; Kim TI; Cho H;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida. [J] . Moon HI, Kim TI, Cho H Bioorganic and Medicinal Chemistry Letters . 2010,第3期

机译：鉴定潜在的和选择性的胶原酶，来自Cretaegus pinnatifida的明胶酶抑制剂。
2. Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase [J] . A J P Docherty, J J Reynolds, J P OConnell, The biochemical journal . 1995,第1期

机译：明胶酶和胶原酶的选择性抑制剂在体外抑制骨吸收
3. Identification of highly selective inhibitors of collagenase-1 from combinatorial libraries of diketopiperazines. [J] . Szardenings AK, Antonenko V, Campbell DA, Journal of Medicinal Chemistry . 1999,第8期

机译：从二酮哌嗪组合库中鉴定胶原酶-1的高选择性抑制剂。
4. Binding Affinities for a Series of Selective Inhibitors of Gelatinase-A Using Molccular Dynamics with a Linear Interaction Energy Approach [C] . 北京大学中医药现代研究中心2001年年会论文集 . 2000

机译：结合亲和力的分子动力学与线性相互作用能方法的明胶酶-A的一系列选择性抑制剂。
5. New Chemical Tools for Glycobiology and Immune Cell-Mediated Diseases: Part I. Identification of Sialyl- and Fucosyltransferase Inhibitors. Part II. Identification of Selective, High-Affinity Siglec Ligands for Cell Targeting. [D] . Rillahan, Cory D. 2012

机译：糖生物学和免疫细胞介导的疾病的新化学工具：第一部分。唾液酸和岩藻糖基转移酶抑制剂的鉴定。第二部分用于细胞靶向的选择性高亲和力Siglec配体的鉴定。
6. Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase. [O] . P A Hill, A J Docherty, K M Bottomley, 1995

机译：明胶酶和胶原酶的选择性抑制剂在体外抑制骨吸收。
7. Inhibition of bone resorption in vitro by selective inhibitors of gelatinase and collagenase. [O] . Hill, P A, Docherty, A J, Bottomley, K M, 1995

机译：明胶酶和胶原酶的选择性抑制剂在体外抑制骨吸收。

Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.

摘要

著录项

相似文献

相关主题

期刊订阅