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Endometrial cancer 2005-2015

机译:子宫内膜癌2005-2015

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Practice Bulletin 149, published in April, 2015, replaces Practice Bulletin 65, published in 2005. This commentary broadly discusses endometrial cancer using Practice Bulletin 149 as a source. The new guidelines reflect current understanding of genetic causes of and risk factors for endometrial cancer. The new Practice Bulletin expands upon contemporary management to include level "A" recommendations regarding the appropriate evaluation of abnormal uterine bleeding to optimize detection and describes appropriate preoperative evaluation. A new surgical staging system was adopted in 2009 to better reflect the behavior of endometrial cancer and align treatment planning. The Practice Bulletin endorses the use of minimally invasive surgery to stage and treat endometrial cancer, which has now been validated in large, prospective trials to dramatically reduce the morbidity of surgery. The Practice Bulletin reflects the ongoing controversy about adjuvant therapy and offers important consensus opinions regarding the appropriate surveillance of endometrial cancer patients after treatment to improve quality of life.
机译:2015年4月发布的Practice Bulletin 149替代了2005年发布的Practice Bulletin65。该评论广泛讨论了使用Practice Bulletin 149作为来源的子宫内膜癌。新指南反映了当前对子宫内膜癌的遗传原因和危险因素的理解。新的《实践公报》在当代管理基础上进行了扩展,包括有关异常子宫出血的适当评估以优化检测的“ A”级建议,并描述了适当的术前评估。 2009年采用了新的手术分期系统,以更好地反映子宫内膜癌的行为并调整治疗计划。 《实践公报》赞同使用微创手术进行子宫内膜癌的分期和治疗,目前已在大型前瞻性试验中得到证实,可以显着降低手术的发病率。该实践公告反映了有关辅助治疗的持续争议,并就治疗后子宫内膜癌患者的适当监测提供了重要的共识性意见,以改善生活质量。

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