Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline

Wei W.-T.; Yeh J.-Y.; Kuo T.-S.; Wu H.-L.

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Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline

机译：芳基硼酸对无环α，β-不饱和化合物的高度对映选择性铑催化的不对称1,4-加成反应：（-）-茚满啉的形式合成

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It's do or diene: Stable chiral bicyclo[2.2.1]diene ligands were synthesized from (-)-5-oxobornyl acetate and utilized in the asymmetric 1,4-addition reaction of arylboronic acids with acyclic α,β- unsaturated compounds. Low catalytic loading of the complex, generated in situ from 1 and [{RhCl(C_2H_4)_2}_2], provides adducts in good to excellent yields and excellent enantioselectivities. This method was used for the formal total synthesis of (-)-indatraline.

机译：是做二烯还是做：稳定的手性双环[2.2.1]二烯配体是由乙酸（-）-5-氧代冰片酯合成的，用于芳基硼酸与无环α，β-不饱和化合物的不对称1,4-加成反应。由1和[{RhCl（C_2H_4）_2} _2]原位生成的配合物的低催化负载量提供了良好至优异收率和优异对映选择性的加合物。该方法用于（-）-茚达林的正式全合成。

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《Chemistry: A European journal》 |2011年第41期|共5页
作者
Wei W.-T.; Yeh J.-Y.; Kuo T.-S.; Wu H.-L.;
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addition reactions; arylboronic acids; asymmetric catalysis; diene ligands; enantioselectivity; indatraline; rhodium;

机译：加成反应芳基硼酸不对称催化二烯配体对映选择性吲哚啉铑;

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1. Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline [J] . Wei W.-T., Yeh J.-Y., Kuo T.-S., Chemistry: A European journal . 2011,第41期

机译：芳基硼酸对无环α，β-不饱和化合物的高度对映选择性铑催化的不对称1,4-加成反应：（-）-茚满啉的形式合成
2. Rhodium-catalyzed highly enantioselective addition of arylboronic acids to cyclic aldimines: Practical asymmetric synthesis of cyclic sulfamidates [J] . WangH., XuM.-H. Synthesis: International Journal of Methods in Synthetic Organic Chemistry . 2013,第15期

机译：铑催化的芳基硼酸的高映选择性加入环族醛胺：循环磺胺酸盐的实际不对称合成
3. Highly Active and Enantioselective Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronie Acid to α,β- Unsaturated Ketone by using Electron-Poor MeO-F_(12)-BIPHEP [J] . Toshinobu Korenaga, Ryota Maenishi, Keigo Hayashi Advanced synthesis & catalysis . 2010,第18期

机译：贫电子的MeO-F_（12）-BIPHEP，高活性和对映选择性的铑催化不对称的1,4-芳基硼酸加成到α，β-不饱和酮上
4. Chiral Rhodium Nanoparticle-catalyzed Asymmetric 1,4- Addition Reactions of Arylboronic Acids with β,γ-Unsaturated α-Ketocarbonyl Compounds [C] . Zhiyuan ZHU, Hiroyuki MIYAMURA, Tomohiro YASUKAWA 日本化学会春季年会講演予稿集 . 2018

机译：手性铑纳米粒子催化的不对称1,4-添加芳基硼酸与β，γ-不饱和α-酮烷基化合物的反应
5. Enantioselective Synthesis of Compounds Containing Bis-Benzylic Quaternary Stereocenters through Palladium-Catalyzed Conjugate Additions of Arylboronic Acids. [D] . Kadam, Abhishek Ashok. 2017

机译：通过钯催化芳基硼酸的共轭加成反应，对映选择性地合成含双苄基四元立体中心的化合物。
6. An N-Linked Bidentate Phosphoramidite Ligand (N-Me-BIPAM) for Rhodium-Catalyzed Asymmetric 14-Addition of Arylboronic Acids to αβ-Unsaturated Ketones [O] . Yasunori Yamamoto, Kazunori Kurihara, Yoshinori Takahashi, 2013

机译：N链双齿亚磷酰胺配体（N-Me-BIPAM）用于铑催化αβ-不饱和酮上芳基硼酸的不对称14-加成
7. An N-Linked Bidentate Phosphoramidite Ligand (N-Me-BIPAM) for Rhodium-Catalyzed Asymmetric 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Ketones [O] . Yamamoto, Yasunori, Kurihara, Kazunori, Takahashi, Yoshinori, 2013

机译：N链双齿亚磷酰胺配体（N-Me-BIPAM），用于铑催化α，β-不饱和酮上芳基硼酸的不对称1,4-加成

Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline

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