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A Single-Wavelength-Emitting Ratiometric Probe Based on Phototriggered Fluorescence Switching of Graphene Quantum Dots

机译:基于石墨烯量子点光触发荧光开关的单波长发射比例探针

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摘要

Ratiometric fluorescent probes are of great importance in research, because a built-in correction for environmental effects can be provided to reduce background interference. However, the traditional ratiometric fluorescent probes require two luminescent materials with different emission bands. Herein a novel ratiometric probe based on a single-wavelength-emitting material is reported. The probe works by regulating the luminescent property of graphene quantum dots with UV illumination as activator. The ratiometric sensor shows high sensitivity and specificity for iron ions. Moreover, the ratiometric sensor was successfully employed to monitor ferritin levels in Sprague Dawley rats with chemical-induced acute liver damage. The proposed singlewavelength ratiometric fluorescent probe may greatly broaden the applicability of ratiometric sensors in diagnostic devices, medical applications, and analytical chemistry.
机译:比例荧光探针在研究中非常重要,因为可以提供对环境影响的内置校正以减少背景干扰。然而,传统的比例荧光探针需要两种具有不同发射带的发光材料。本文报道了一种基于发射单波长材料的新型比例式探针。该探针通过使用紫外线作为活化剂来调节石墨烯量子点的发光特性而工作。比例传感器显示出对铁离子的高灵敏度和特异性。此外,比例传感器已成功用于监测化学性急性肝损伤的Sprague Dawley大鼠的铁蛋白水平。提出的单波长比例荧光探针可以大大拓宽比例传感器在诊断设备,医疗应用和分析化学中的适用性。

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