• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chemistry: A European journal >Room-Temperature ortho-Alkoxylation and -Halogenation of NTosylbenzamides by Using Palladium(II)-Catalyzed C-H Activation
【24h】

Room-Temperature ortho-Alkoxylation and -Halogenation of NTosylbenzamides by Using Palladium(II)-Catalyzed C-H Activation

机译：钯（II）催化的C-H活化在室温下对NTosylbenzamides进行邻位烷氧基化和卤代反应

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The N-tosylcarboxamide group can direct the room-temperature palladium-catalyzed CüH alkoxylation and halogenation of substituted arenes in a simple and mild procedure. The room-temperature stoichiometric cyclopalladation of N-tosylbenzamide was first studied, and the ability of the palladacycle to react with oxidants to form CüX and Cü O bonds under mild conditions was demonstrated. The reaction conditions were then adapted to promote room-temperature ortho-alkoxylations and ortho-halogenations of Ntosylbenzamides using palladium as catalyst. The scope and limitation of both alkoxylations and halogenations was studied and the subsequent functional transformation of the Ntosylcarboxamide group through nucleophilic additions was evaluated. This methodology offers a simple and mild route to diversely functionalized arenes.
机译：N-甲苯磺酰胺基团可以通过简单，温和的步骤指导室温钯催化的CüH烷氧基化和取代芳烃的卤化。首先研究了N-甲苯磺酰基苯甲酰胺的室温化学计量环palpalladation，并证明了palladacycle在温和条件下与氧化剂反应形成CüX和CüO键的能力。然后使反应条件适应以使用钯作为催化剂促进Ntosylbenzamides的室温邻位烷氧基化和邻位卤化。研究了烷氧基化和卤化的范围和局限性，并评估了Ntosylcarboxamide基团通过亲核加成后的功能转化。这种方法学提供了一条简单而温和的途径来开发功能多样的芳烃。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号