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首页> 外文期刊>Current Science: A Fortnightly Journal of Research >Diagnostic value of oscillation technique for chronic obstructive pulmonary disease: a meta-analysis
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Diagnostic value of oscillation technique for chronic obstructive pulmonary disease: a meta-analysis

机译：振荡技术对慢性阻塞性肺疾病的诊断价值：荟萃分析

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摘要

Many studies have investigated the usefulness of oscillation technique, including forced oscillation technique (FOT) and impulse oscillation technique (IOS), for the diagnosis of chronic obstructive pulmonary disease (COPD). However, the overall diagnostic accuracy of oscillation technique for COPD remains unclear. The aim of the present meta-analysis was to determine the overall accuracy of oscillation techniques for diagnosis of COPD. We performed a systematic search in PubMed and Embase. Data on sensitivity, specificity, positiveegative likelihood ratio (PLR/NLR), and diagnostic odds ratio (DOR) were pooled. Summary receiver operating characteristic (SROC) curves and area under the curve (AUC) were used to summarize overall test performance. Six studies met our inclusion criteria. Summary estimates for oscillation technique in the diagnosis of COPD are as follows: sensitivity - 0.77 (95% CI 0.70-0.83; I-2 = 87.6%); specificity - 0.85 (95% CI 0.81-0.88; I-2 = 58.4%); PLR - 5.99 (95% CI 2.91-12.34); NLR -0.16 (95% CI 0.005-0.47); DOR - 47.95 (95% CI 9.99-230.17) and AUC - 0.96. Pooled estimates for FOT were as follows: sensitivity 0.94 (95% CI 0.86-0.98), specificity 0.94 (95% CI 0.86-0.98), PLR 11.48 (95% CI 5.17-25.48), NLR 0.08 (95% CI 0.03-0.17), DOR 221.8 (95% CI 58.39-842.5), and AUC 0.98. Given its easy to perform and subject-independent nature, our metaanalysis suggests a potential role for oscillation technique in diagnosis of COPD, especially FOT.
机译：许多研究已经研究了包括强制振荡技术（FOT）和脉冲振荡技术（IOS）在内的振荡技术在诊断慢性阻塞性肺疾病（COPD）中的有用性。但是，COPD振荡技术的整体诊断准确性仍不清楚。本荟萃分析的目的是确定用于诊断COPD的振荡技术的总体准确性。我们在PubMed和Embase中进行了系统的搜索。收集有关敏感性，特异性，阳性/阴性似然比（PLR / NLR）和诊断比值比（DOR）的数据。摘要接收器工作特性（SROC）曲线和曲线下面积（AUC）用于总结总体测试性能。六项研究符合我们的纳入标准。诊断COPD的振荡技术概述如下：敏感性-0.77（95％CI 0.70-0.83; I-2 = 87.6％）;特异性-0.85（95％CI 0.81-0.88; I-2 = 58.4％）; PLR-5.99（95％CI 2.91-12.34）; NLR -0.16（95％CI 0.005-0.47）; DOR-47.95（95％CI 9.99-230.17）和AUC-0.96。 FOT的汇总估算如下：灵敏度0.94（95％CI 0.86-0.98），特异性0.94（95％CI 0.86-0.98），PLR 11.48（95％CI 5.17-25.48），NLR 0.08（95％CI 0.03-0.17） ），DOR 221.8（95％CI 58.39-842.5）和AUC 0.98。鉴于其易于执行且与受试者无关的性质，我们的荟萃分析表明，振荡技术在诊断COPD，尤其是FOT中具有潜在的作用。

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