首页> 外文期刊>Biophysics >Properties of Hybridization Isothermsupon Binding of Ligands on Microchips
【24h】

Properties of Hybridization Isothermsupon Binding of Ligands on Microchips

机译:芯片上配体的杂交等温线结合特性

获取原文
获取原文并翻译 | 示例
           

摘要

A simple thermodynamic model describing microarray oligo—target hybridization has been con-structed. The relationship between the hybridization signal intensity and Gibbs free energy for oligo—targetduplex formation has been considered. The behavior of this function, which we called energy hybridizationisotherm, in response to target concentration change was modeled at different ratios of oligo/target concen-trations. The results of modeling were compared with the relevant and currently available data from microar-ray adsorption experiments.
机译:已经构建了描述微阵列寡核苷酸-靶标杂交的简单热力学模型。已经考虑了杂交信号强度与吉布斯自由能之间的寡聚-目标双链体形成之间的关系。该功能的行为(我们称为能量杂交等温线)响应目标浓度变化的模型是在寡核苷酸/目标浓度的不同比率下进行的。将建模结果与微弧吸附实验的相关数据和当前可用数据进行了比较。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号