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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Hybrid-including Endoscopic versus Open Hepatic Resection for Patients with Hepatocellular Carcinoma Meeting the Milan Criteria: A Propensity Case-matched Analysis
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Hybrid-including Endoscopic versus Open Hepatic Resection for Patients with Hepatocellular Carcinoma Meeting the Milan Criteria: A Propensity Case-matched Analysis

机译:符合米兰标准的肝细胞癌患者的混合手术(包括内镜与开放式肝切除术):倾向病例匹配分析

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Aim: To clarify the surgical outcome of patients who underwent endoscopic hepatectomy (EH) compared to those of conventional open hepatectomy (OH) for hepatocellular carcinoma (HCC). Patients and Methods: Between 1999 and 2011, 269 HCC patients meeting the Milan criteria were divided into EH (n=89) and OH groups (n=180). To equalize the background covariates. a one-to-one propensity case-matched analysis was used. Results: With propensity matching, 52 EH and 52 OH patients showed comparable preoperative clinical characteristics. The operation time (320 min, p=0.049) and the median blood loss (180 g, p<0.001) was significantly lesser with EH, while the median postoperative hospital stay (11 days, p=0.002) was significantly shorter for EH. The cumulative disease-free and overall survival rates were equivalent in both groups. Conclusion: EH for HCC patients meeting the Milan criteria is less invasive and might provide an equivalent disease-free and overall survival when compared to conventional OH.
机译:目的:为了阐明与传统的开放式肝切除术(OH)相比,接受内窥镜肝切除术(EH)的患者对肝细胞癌(HCC)的手术效果。患者和方法:在1999年至2011年之间,将269例符合米兰标准的HCC患者分为EH组(n = 89)和OH组(n = 180)。为了均衡背景协变量。使用一对一的倾向病例匹配分析。结果:通过倾向匹配,52例EH和52 OH患者表现出可比的术前临床特征。 EH的手术时间(320分钟,p = 0.049)和中位失血量(180 g,p <0.001)显着缩短,而EH的中位术后住院时间(11天,p = 0.002)显着缩短。两组的无病累积生存率和总生存率相等。结论:与常规OH相比,符合Milan标准的HCC患者的EH侵入性较小,并且可以提供同等的无病生存率和总体生存率。

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