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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Adequate Margins to Prevent Local Re-recurrence of Rectal Cancer: Viewpoint of Pathological Findings
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Adequate Margins to Prevent Local Re-recurrence of Rectal Cancer: Viewpoint of Pathological Findings

机译：足够的利润率来预防直肠癌的局部复发：病理结果的观点

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Background: A sufficient surgical margin is critical for preventing re-recurrence and achieving R0 status after resection of a local recurrence of rectal cancer (LRRC). Patients and Methods: Re-recurrence-free survival was analyzed in 110 cases of LRRC according to histological type of primary lesion. The circumferential resection margin (CRM) was classified as 'R1' (x=0 mu m), 'R0 shortness' (0 mu m = 2,000 mu m). The histological change from the primary lesion to the recurrent lesion was classified as 'No change pattern', from well-to moderately-differentiated (W/M) to an expanding lesion; as 'Change pattern', from W/M to an infiltrating lesion. Results: Re-recurrence-free survival was better in 'R0 longness' than 'R0 shortness' groups and showed that 'No change pattern' cases had considerably better prognosis than 'Change pattern' cases. Conclusion: Ensuring a CRM >2,000 mu m during resection of LRRC is more likely to prevent rerecurrence. Cases with poorly differentiated carcinoma from the primary lesion to the recurrent lesion tend to have poor prognoses.
机译：背景：足够的手术切缘对于预防局部直肠癌（LRRC）切除术后的复发和达到R0状态至关重要。患者和方法：根据原发灶的组织学类型分析110例LRRC患者的无复发生存率。圆周切除切缘（CRM）分为``R1''（x = 0微米），``R0短度''（0微米 = 2,000微米） 。从原发性病变到复发性病变的组织学变化被分类为“无变化模式”，从高分化到中分化（W / M）再到扩大病变。作为“改变模式”，从W / M到浸润性病变。结果：“ R0长”组的无复发生存率优于“ R0短”组，表明“无变化模式”病例的预后要好于“变化模式”病例。结论：LRRC切除期间确保CRM> 2,000μm更可能防止复发。从原发性病变到复发性病变的分化较差的癌症患者的预后往往较差。

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