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Analysis of interferograms of multi-layered biological samples obtained from full field optical coherence tomography systems

机译：从全场光学相干断层扫描系统获得的多层生物样品的干涉图分析

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Several methods were developed in the past to analyze interferograms produced by optical coherence tomography, and successfully applied to simulated or animated samples. However, these techniques do not cope with noisy and distorted interferograms from biological tissues. In this paper, known techniques, including the fast Fourier transform and several variations of the continuous wavelet transform, were employed to analyze the interferogram data. However, to cope with the difficulties in biological data, pre- and post-processing procedures and adaptive thresholding were developed to provide stability and robustness. Additionally, three-dimensional structural models of the biological samples were constructed, and revealed information like the number and locations of interfaces, the layer thickness and pattern, and abnormalities.
机译：过去开发了几种方法来分析光学相干断层扫描产生的干涉图，并将其成功地应用于模拟或动画样本。但是，这些技术不能应对来自生物组织的嘈杂和扭曲的干涉图。在本文中，采用了包括快速傅立叶变换和连续小波变换的几种变体在内的已知技术来分析干涉图数据。然而，为了应对生物数据中的困难，开发了预处理和后处理程序以及自适应阈值处理来提供稳定性和鲁棒性。另外，构建了生物样品的三维结构模型，并揭示了诸如界面的数量和位置，层的厚度和图案以及异常等信息。

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