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首页> 外文期刊>Contraception >When can a woman resume or initiate contraception after taking emergency contraceptive pills? A systematic review
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When can a woman resume or initiate contraception after taking emergency contraceptive pills? A systematic review

机译：女人服用紧急避孕药后什么时候可以恢复或开始避孕？系统评价

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Background: Hormonal emergency contraception can postpone ovulation, making a woman vulnerable to pregnancy later in the same cycle. However, concern exists as to whether concurrently administered emergency contraception pills (ECP) and other hormonal methods of contraception may affect the effectiveness of both medications. Study Design: A systematic review of the literature using PubMed and the Cochrane databases was performed to identify articles concerning the resumption or initiation of regular contraception within the same cycle as ECP use. We searched for articles in any language, published between 1980 and April 2012 and included all methods of emergency contraception pills available in the USA. Results: The search strategy identified 184 articles in the PubMed and Cochrane databases, of which none met inclusion criteria. Conclusion: The drug manufacturer advises continuation or initiation of routine contraception as soon as possible after use of ulipristal acetate, with concomitant use of a reliable barrier method until next menses. However, a theoretical concern exists that given ulipristal acetate's function as a selective progesterone receptor modulator, coadministration of a progestin could decrease its effectiveness as an emergency contraceptive. Initiation of hormonal contraception following levonorgestrel or the Yuzpe regimen for emergency contraception carries no similar concern for decreased method effectiveness.
机译：背景：激素紧急避孕可以推迟排卵，使妇女在同一周期的后期容易受孕。然而，存在关于同时服用紧急避孕药（ECP）和其他激素避孕方法是否会影响两种药物有效性的担忧。研究设计：使用PubMed和Cochrane数据库对文献进行系统的回顾，以鉴定与ECP使用同一周期内恢复或开始常规避孕的文章。我们搜索了1980年至2012年4月之间发布的任何语言的文章，其中包括美国提供的所有紧急避孕药方法。结果：搜索策略在PubMed和Cochrane数据库中确定了184篇文章，没有一篇符合纳入标准。结论：药物制造商建议在使用醋酸乌利司他后尽快或继续进行常规避孕，并同时使用可靠的屏障方法直到下一次月经来潮。然而，存在理论上的担忧，即鉴于乙酸乌利司他作为选择性孕激素受体调节剂的功能，孕激素的共同给药可能会降低其作为紧急避孕药的有效性。左炔诺孕酮或Yuzpe方案用于紧急避孕后开始激素避孕没有引起方法有效性降低的类似担忧。

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