Three-unit semicircles curve: A compact 3D graphical representation of DNA sequences based on classifications of nucleotides

Li Y.; Qin Y.; Zheng X.; Zhang Y.

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Three-unit semicircles curve: A compact 3D graphical representation of DNA sequences based on classifications of nucleotides

机译：三单元半圆曲线：基于核苷酸分类的DNA序列的紧凑3D图形表示

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摘要

A new three-dimensional graphical representation of DNA sequences, three-unit semicircles (TUS)-curve, which maps a given sequence into a dot sequences embedded in three-unit semicircles, is proposed based on three biclassifications of nucleotides. TUS-curve has the merit of compactness and could avoid the degeneracy and loss of information. The geometrical center of the curve, which indicates the distribution of base frequencies of the corresponding DNA sequence, is extracted and applied to analyze the similarity of various species. Phylogenetic tree of 11 species based on their first exons of β-globin genes showed that the TUS-curve is a powerful tool to get valuable biological information.

机译：基于核苷酸的三个双分类，提出了一种新的三维DNA序列三维图形表示法，即三单元半圆（TUS）曲线，该曲线将给定序列映射到嵌入三单元半圆中的点序列。 TUS曲线具有紧凑性的优点，可以避免退化和信息丢失。提取指示相应DNA序列基本频率分布的曲线的几何中心，并将其用于分析各种物种的相似性。 11种物种的系统发育树基于它们的第一个β-珠蛋白基因外显子显示，TUS曲线是获取有价值的生物学信息的有力工具。

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《International Journal of Quantum Chemistry》 |2012年第10期|共6页
作者
Li Y.; Qin Y.; Zheng X.; Zhang Y.;
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正文语种 eng
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关键词
biclassification; graphical representation; invariant; phylogenetic tree; similarity analysis;

机译：双分类;图形表示;不变式;系统树;相似性分析;

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专利

1. Three-unit semicircles curve: A compact 3D graphical representation of DNA sequences based on classifications of nucleotides [J] . Li Y., Qin Y., Zheng X., International Journal of Quantum Chemistry . 2012,第9a10期

机译：三单元半圆曲线：基于核苷酸分类的DNA序列的紧凑3D图形表示
2. Wormstep: An improved compact graphical representation of DNA sequences based on worm curve [J] . Zhang Z., Zeng X., Song T., Journal of computational and theoretical nanoscience . 2013,第1期

机译：Wormstep：基于蠕虫曲线的DNA序列的紧凑紧凑图形表示
3. A group of 3D graphical representation of DNA sequences based on dual nucleotides [J] . Cao Z, Liao B, Li RF International Journal of Quantum Chemistry . 2008,第9期

机译：一组基于双核苷酸的DNA序列的3D图形表示
4. Similarity/dissimilarity analysis of DNA sequences based on a 3D graphical representation [C] . Hailan Huang, Long Shi The 3rd International Conference on Bioinformatics and Biomedical Engineering(iCBBE 2009)(第三届生物信息与生物医学工程国际会议）论文集 . 2009

机译：基于3D图形表示法的DNA序列相似性/不相似性分析
5. Impact of DNA Conformation and Base Sequence Context on Efficiencies of Nucleotide Excision Repair of Bulky DNA Adducts. [D] . Reeves, Dara Akosua. 2010

机译：DNA构象和碱基序列背景对大块DNA加合物的核苷酸切除修复效率的影响。
6. Three 3D graphical representations of DNA primary sequences based on the classifications of DNA bases and their applications [O] . Guosen Xie, Zhongxi Mo -1

机译：基于DNA碱基的分类及其应用的3D DNA初级序列的3D图形表示
7. Three 3D graphical representations of DNA primary sequences based on the classifications of DNA bases and their applications [O] . Guosen Xie, Zhongxi Mo 2011

机译：基于DNA基础和应用的分类，DNA初级序列的三个3D图形表示

Three-unit semicircles curve: A compact 3D graphical representation of DNA sequences based on classifications of nucleotides

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