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Catalytic kinetics of single gold nanoparticles observed via optical microwell arrays

机译:通过光学微孔阵列观察到的单个金纳米颗粒的催化动力学

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Catalytic activities and kinetics are measured at the single-particle level for gold nanoparticles catalyzing a fluorogenic oxidation reaction. This measurement is accomplished by confining the reactions in optically addressable microwell arrays. Citrate-capped gold nanoparticles are isolated in sealed similar to 70 fL microwells along with a substrate, and the accumulation of a fluorescent product over time is observed. Thousands of reactions are measured in parallel. Catalytic activities are calculated for each nanoparticle and the activity distribution is analyzed.
机译:在单颗粒水平上测量了催化荧光氧化反应的金纳米颗粒的催化活性和动力学。通过将反应限制在光学可寻址微孔阵列中来完成此测量。将柠檬酸盐封端的金纳米颗粒与底物一起在类似于70 fL微孔的密封中分离,观察到荧光产物随时间的积累。并行测量数千个反应。计算每个纳米颗粒的催化活性,并分析活性分布。

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