Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

Ahmadov Tevhide Ozkaya; Ding Rui; Zhang Jinnan; Wang Peng; Tang Hong; Zhang Peng

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Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

机译：银纳米颗粒增强型混合光敏剂，用于多药耐药金黄色葡萄球菌（MRSA）的光灭活

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In recent years, multidrug-resistant Staphylococcus aureus (MRSA) has become one of the main bacteria associated with serious diseases in both hospital and the community. Herein we report that a type of hybrid photosensitizers consisting of silver nanoparticles and photosensitizing molecules display outstanding photodynamic inactivation capability against MRSA, with an enhanced killing efficacy of up to similar to 6 orders of magnitude under the experimental conditions. The results support that such hybrid photosensitizers can be used for photodynamic inactivation of MRSA without involving antibiotics.

机译：近年来，耐多药金黄色葡萄球菌（MRSA）已成为医院和社区中与严重疾病相关的主要细菌之一。在本文中，我们报道了一种由银纳米颗粒和光敏分子组成的杂化光敏剂，其对MRSA表现出出色的光动力学灭活能力，在实验条件下的杀灭效力高达6个数量级。结果支持这种杂化光敏剂可用于不涉及抗生素的MRSA的光动力学灭活。

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《RSC Advances》 |2016年第59期|共4页
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Ahmadov Tevhide Ozkaya; Ding Rui; Zhang Jinnan; Wang Peng; Tang Hong; Zhang Peng;
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1. Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA) [J] . Ahmadov Tevhide Ozkaya, Ding Rui, Zhang Jinnan, RSC Advances . 2016,第59期

机译：银纳米颗粒增强型混合光敏剂，用于多药耐药金黄色葡萄球菌（MRSA）的光灭活
2. Selective and Efficient Photoinactivation of Intracellular Staphylococcus aureus and MRSA with Little Accumulation of Drug Resistance: Application of a Ru(II) Complex with Photolabile Ligands [J] . Sun Weize, Jian Yao, Zhou Mengxue, Journal of Medicinal Chemistry . 2021,第11期

机译：细胞内金黄色葡萄球菌和MRSA的选择性和高效的光灭活，耐药少累积：ru（ii）复合物与光型配体的应用
3. Photodynamic antimicrobial chemotherapy of asymmetric porphyrin-silver conjugates towards photoinactivation of Staphylococcus aureus [J] . Journal of Coordination Chemistry . 2020,第3a4期

机译：光学卟啉银缀合物的光动力抗菌化疗朝向金黄色葡萄球菌的光灭活
4. Synthesis and Characterization of Biogenic Selenium Nanoparticles with Antimicrobial Properties Made by Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Pseudomonas aeruginosa. [C] . David Medina, Thomas J. Webster Society for Biomaterials annual meeting and exposition . 2018

机译：金黄色葡萄球菌，耐甲氧西林金黄色葡萄球菌（MRSA），大肠杆菌和铜绿假单胞菌制成的具有抗菌特性的生物硒纳米粒子的合成与表征。
5. Detection and molecular typing of methicillinsusceptible Staphylococcus aureus (MSSA) and methicillinresistant Staphylococcus aureus (MRSA) [D] . Velasco, Valeria 2015

机译：耐甲氧西林金黄色葡萄球菌（MSSA）和耐甲氧西林金黄色葡萄球菌（MRSA）的检测和分子分型
6. Modulation of the Antibiotic Activity by the Mauritia flexuosa (Buriti) Fixed Oil against Methicillin-Resistant Staphylococcus Aureus (MRSA) and Other Multidrug-Resistant (MDR) Bacterial Strains [O] . Yara Faustino Pereira, Maria do Socorro Costa, Saulo Relison Tintino, 2018

机译：柔毛（Bururi）固定油对耐甲氧西林金黄色葡萄球菌（MRSA）和其他耐多药（MDR）细菌菌株的抗生素活性的调节
7. Aplicação de estudos de QSAR-2D em derivados 5-nitro-2-tiofilidênicos com atividade antimicrobiana frente a Staphylococcus aureus multi-resistente (MRSA) 2D QSAR studies of 5-nitro-2-thiophylidene derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus (MRSA) [O] . Andrea Masunari, Leoberto Costa Tavares 2006

机译：QsaR-2D研究在5-硝基-2-硫代乙烯基衍生物上的应用，具有抗多重耐药金黄色葡萄球菌（mRsa）的抗菌活性2D-QsaR研究5-硝基-2-硫代亚砜衍生物具有抗多药耐药性金黄色葡萄球菌的抗菌活性（mRsa）

Silver nanoparticle-enhanced hybrid photosensitizer for photoinactivation of multidrug-resistant Staphylococcus aureus (MRSA)

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