A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C-O and C-N bond formation approach

Guo Pengfeng; Wang Changcheng; Chen Ya; Ou Caijun; Jiang Hangqi; Chen Weifeng; Chen Weixin; Cao Hua

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A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C-O and C-N bond formation approach

机译：用于合成呋喃的一锅无金属三组分多米诺骨牌序列：有效的C-O和C-N键形成方法

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A novel one pot, metal-free, three-component domino reaction for the formation of furan derivatives has been developed from 3-phenylpropiolaldehyde, 1,3-dicarbonyl compounds and aromatic amine or aliphatic acid. This transformation provided a general and facile access to the construction of C-O andC-N bonds to prepare various bioactive furans in good yields.

机译：由3-苯基丙醛，1，3-二羰基化合物和芳族胺或脂族酸开发了一种新颖的无罐，无金属，三组分多米诺反应，用于形成呋喃衍生物。这种转化为构建C-O和C-N键提供了一个普遍而又容易的途径，以高产率制备各种生物活性呋喃。

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《RSC Advances》 |2016年第46期|共5页
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Guo Pengfeng; Wang Changcheng; Chen Ya; Ou Caijun; Jiang Hangqi; Chen Weifeng; Chen Weixin; Cao Hua;
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1. A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C-O and C-N bond formation approach [J] . Guo Pengfeng, Wang Changcheng, Chen Ya, RSC Advances . 2016,第46期

机译：用于合成呋喃的一锅无金属三组分多米诺骨牌序列：有效的C-O和C-N键形成方法
2. One-Pot Regiospecific Synthesis of Imidazo[1,2-a]pyridines: A Novel, Metal-Free, Three-Component Reaction for the Formation of C-N, C-O, and C-S Bonds [J] . Hua Cao, Xiaohang Liu, Limin Zhao, Organic letters . 2014,第1期

机译：一锅区域特异性合成咪唑并[1,2-a]吡啶：形成C-N，C-O和C-S键的新型无金属三组分反应
3. One-Pot Regiospecific Synthesis of Imidazo[1,2-a]pyridines: A Novel, Metal-Free, Three-Component Reaction for the Formation of C-N, C-O, and C-S Bonds [J] . Hua Cao, Xiaohang Liu, Limin Zhao, Organic letters . 2014,第1期

机译：一锅区域特异性合成咪唑并[1,2-a]吡啶：形成C-N，C-O和C-S键的新型无金属三组分反应
4. Synthesis of Heterocyclic Compounds via Nickel-Catalyzed Addition of C-N and C-O Bond to Alkynes [C] . Takuya Kurahashi, Seijiro Matsubara Symposium on Organometallic Chemistry . 2008

机译：通过镍催化的C-N和C-O键合成杂环化合物至炔烃
5. Catalytic C-C (C-N) Bond Formation and C-O Bond Cleavage by Pincer-Ligated Iridium Complexes [D] . Li, Bo. 2019

机译：掺杂剂铱络合物催化C-C（C-N）键合形成和C-O键切割
6. Regioselectivity and Mechanism of Synthesizing N-Substituted 2-Pyridones and 2-Substituted Pyridines via Metal-Free C-O and C-N Bond-Cleaving of Oxazoline32-apyridiniums [O] . Bo Li, Susu Xue, Yang Yang, -1

机译：通过无金属恶唑啉32-a吡啶鎓的无金属C-O和C-N键裂解合成N-取代的2-吡啶酮和2-取代的吡啶的区域选择性和机理
7. Three-Component One-Pot Approach to Highly Efficient and Sustainable Synthesis of the Functionalized Quinolones via Linear/Branched Domino Protocols, Key Synthetic Methods for the Floxacin of Quinolone Drugs [O] . Hairui Bai, Fujun Liu, Xiaojing Wang, 2018

机译：通过线性/支链Domino方案，喹啉药物氟甲酰胺的关键合成方法对高效和可持续合成官能化喹诺酮类的三组分一锅方法。

A one pot, metal-free, three-component domino sequence for the synthesis of furans: an efficient C-O and C-N bond formation approach

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