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首页> 外文期刊>Cornea >Amniotic membrane transplantation for ocular surface reconstruction.
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Amniotic membrane transplantation for ocular surface reconstruction.

机译：羊膜移植用于眼表重建。

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The amniotic membrane, composed of 3 layers, the epithelium, basement membrane, and the stroma, was first used along with the chorion as a biologic membrane to promote healing of skin burns in 1910. In ophthalmology, it was used in 1940 in the management of conjunctival defects. Its revival in the 1990s was due to its ability to reduce ocular surface inflammation and scarring, promote rapid epithelialization due to the presence of growth factors, and antimicrobial properties. This has resulted in its application in several ocular disorders. A review of the literature shows that amniotic membrane is definitely beneficial in some but not all pathology. The future of amniotic membrane transplantation is very exciting, especially in the field of limbal stem cell research. However, further work is needed to elucidate whether it functions merely as a biologic contact lens or whether it has additional benefits.
机译：羊膜由上皮，基底膜和间质三层组成，在1910年首次与绒毛膜一起用作生物膜，以促进皮肤烧伤的愈合。在眼科，1940年用于管理结膜缺损。其在1990年代的复兴归因于其减少眼表炎症和疤痕，由于存在生长因子而促进快速上皮形成以及抗菌特性的能力。这导致其在几种眼疾中的应用。文献综述表明，羊膜在某些但不是全部病理学中肯定是有益的。羊膜移植的未来非常令人兴奋，特别是在角膜缘干细胞研究领域。但是，需要进一步的工作来阐明它是否仅用作生物接触镜或是否具有其他好处。

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