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首页> 外文期刊>Cornea >The epidemiological features and laboratory results of fungal keratitis: a 10-year review at a referral eye care center in South India.
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The epidemiological features and laboratory results of fungal keratitis: a 10-year review at a referral eye care center in South India.

机译：真菌性角膜炎的流行病学特征和实验室检查结果：在南印度的转诊眼保健中心进行的十年回顾。

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PURPOSE: To report the epidemiological features and laboratory results of 1,352 cases of fungal keratitis diagnosed at the L.V. Prasad Eye Institute (LVPEI) in south India. METHODS: The medical and microbiology records of 1,352 culture proven cases (1,354 eyes) of fungal keratitis diagnosed at the LVPEI between January 1991 to December 2000 was retrospectively reviewed for demographic features, risk factors, seasonal variation, and laboratory findings. RESULTS: Males (962) were affected significantly more (p< 0.0001) than females (390). Of 1,352 patients, 853 (64.4%) were in the younger age group (16-49 years). Ocular trauma predisposed to infection in 736 (54.4%) of 1,354 eyes. There was a higher incidence of fungal keratitis during the monsoon and winter than summer. A fungal cause was established by smears of corneal scrapings in 1,277 (95.4%) eyes. The potassium hydroxide preparation (KOH), Calcofluor white (CFW), Gram-, and Giemsa-stained smears revealed fungus in 1,219 (91.0%), 1,224 (91.4%), 1,181 (88.2%), and 1,139 (85.1%) eyes, respectively. Fusarium(506, 37.2%) and Aspergillusspecies (417, 30.7%) predominated the hyaline fungal spectrum (1,133) and Curvulariaspecies (39, 2.8%) were the highest among the dematiaceous isolates (218). CONCLUSIONS: To the best of our knowledge, this review presents the epidemiological features and laboratory results of the largest series of fungal keratitis ever reported in the literature. Keratomycosis is predominant in young adults with trauma as the major predisposing factor. With fungal keratitis being a major ophthalmologic problem in the tropical regions of the world, data available on the epidemiological features of a large series would greatly help medical practitioners at primary and secondary health care centers in the management of the disease. A simple KOH preparation of corneal scraping alone is highly beneficial in confirming the diagnosis.
机译：目的：报告在LV诊断的1352例真菌性角膜炎的流行病学特征和实验室检查结果。印度南部的普拉萨德眼科研究所（LVPEI）。方法：回顾性地回顾了1991年1月至2000年12月在LVPEI诊断出的1352例经文化证实的真菌性角膜炎病例的医学和微生物学记录（人口统计学特征，危险因素，季节性变化和实验室检查结果）。结果：男性（962）受到的影响明显大于女性（390）（p <0.0001）。在1,352名患者中，有853名（64.4％）位于年龄较小的年龄段（16-49岁）。眼外伤易感染1,354眼中的736（54.4％）。在季风和冬季，真菌性角膜炎的发病率高于夏季。在1277眼（95.4％）的眼中涂了角膜刮片，确定为真菌病因。氢氧化钾制剂（KOH），钙荧光白（CFW），革兰氏和吉姆萨氏染色涂片显示真菌在1,219（91.0％），1,224（91.4％），1,181（88.2％）和1,139（85.1％）眼中， 分别。镰刀菌属（506，37.2％）和曲霉菌属（417，30.7％）在透明菌谱中占主导地位（1,133），弯孢菌属菌种（39，2.8％）在皮肤病菌分离株中最高（218）。结论：就我们所知，本综述介绍了文献中报道的最大系列真菌性角膜炎的流行病学特征和实验室结果。角膜溃疡主要发生在以创伤为主要诱因的年轻成年人中。由于真菌性角膜炎是世界热带地区的主要眼科问题，有关一系列大流行病学特征的可用数据将极大地帮助初级和二级保健中心的执业医师治疗该疾病。单独的简单KOH制剂刮除角膜对确认诊断非常有帮助。

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