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首页> 外文期刊>Cornea >Randomized, double-masked clinical trial evaluating corneal endothelial cell loss after cataract extraction and intraocular lens implantation: Fluid-based system versus ultrasound phacoemulsification.
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Randomized, double-masked clinical trial evaluating corneal endothelial cell loss after cataract extraction and intraocular lens implantation: Fluid-based system versus ultrasound phacoemulsification.

机译：评估白内障摘除和人工晶状体植入后角膜内皮细胞损失的随机，双掩盖临床试验：基于液的系统与超声超声乳化术。

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摘要

PURPOSE: To assess the endothelial cell loss after cataract extraction using a fluid-based system and compare it with conventional ultrasound. METHODS: A total of 46 eyes of 23 patients with up to 3+ bilateral cataract were included. The first eye was randomized to either fluid-based system or conventional ultrasound, and the fellow eye received the alternate system. Visual acuity and ultrasound pachymetry were measured preoperatively and at 1 day, 1 week, and 1 and 3 months postoperatively. Specular microscopy was performed preoperatively and 3 months after the surgery. Data was analyzed using the paired t test and Wilcoxon signed rank test. A P value less than 0.05 was considered statistically significant. RESULTS: Postoperatively, no significant differences were found among the groups. However, there was a significant difference (P < 0.01, analysis of variance with Tukey as posttest) in corneal pachymetry at day 1 after the surgery compared with baseline in both groups. There was a 6.3% and 7.9% loss of endothelial cells in the fluid-based system and ultrasound group, respectively. CONCLUSION: Visual acuity, pachymetry, and endothelial cell loss after cataract extraction and intraocular lens implantation using a fluid-based system is similar to conventional ultrasound.
机译：目的：评估使用基于液压系统的白内障摘除后内皮细胞的损失，并将其与常规超声进行比较。方法：共纳入23例双侧白内障3+患者的46只眼。第一只眼睛被随机分配到基于流体的系统或常规超声检查中，另一只眼睛接受了另一种系统。术前和术后1天，1周以及1和3个月测量视力和超声测厚法。术前和手术后3个月进行镜检镜检查。使用配对t检验和Wilcoxon符号秩检验对数据进行分析。 P值小于0.05被认为具有统计学意义。结果：术后两组之间无明显差异。然而，与基线相比，两组术后第1天角膜测厚法存在显着差异（P <0.01，用Tukey作为后验方差分析）。液基系统和超声治疗组的内皮细胞损失分别为6.3％和7.9％。结论：使用基于流体的系统进行白内障摘除和人工晶状体植入后的视敏度，测厚法和内皮细胞损失与常规超声相似。

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