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首页> 外文期刊>Controlled clinical trials >A simple alternative confidence interval for the difference between two proportions.
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A simple alternative confidence interval for the difference between two proportions.

机译：两个比例之间差异的简单替代置信区间。

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摘要

The difference between two proportions is often the focus of interest in prospective comparative studies such as randomized controlled trials that have a binary outcome. Consequently, interval estimation for this parameter has received considerable attention in the literature. A hybrid procedure resulting from combining two sets of confidence limits for a single proportion as proposed by Newcombe has been previously recommended for this purpose because of its superior properties and relative simplicity. In this paper, we propose a simple alternative approach based on Fisher's z transformation. The results of an exact evaluation study show that this new procedure performs as well as Newcombe's procedure in terms of percent coverage and expected confidence interval width. Several examples are presented.
机译：两个比例之间的差异通常是前瞻性比较研究（例如具有二元结果的随机对照试验）关注的焦点。因此，在文献中对此参数的间隔估计已引起相当大的关注。为此，先前已建议将由Newcombe提出的将两个置信度限制集合并为一个比例而产生的混合过程，因为它具有优越的性能和相对简单的特性。在本文中，我们提出了一种基于Fisher的z变换的简单替代方法。精确评估研究的结果表明，就覆盖率百分比和预期置信区间宽度而言，此新程序的性能与Newcombe的程序相同。给出了几个例子。

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