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The challenge of malaria eradication in the twenty-first century: Research linked to operations is the key

机译:二十一世纪消除疟疾的挑战:与行动相关的研究是关键

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Interest and support for malaria control, eradication, and research has increased greatly over the past decade. This has resulted from appreciation of the huge medical, social, and economic burden that malaria exacts from endemic populations. Recent breakthroughs in drug development (artemisinin-based combination treatments), preventive interventions (long-lasting, insecticide-treated bed nets), improved diagnosis (rapid diagnostic tests), and community mobilization have resulted in deployment of newantimalarial tools. National programs supported by the Global Fund to Fight AIDS, Tuberculosis and Malaria, the U.S. President's Malaria Initiative, and other donors have resulted in substantial reductions in malaria morbidity and mortality. Bill and Melinda Gates have given great impetus to eradication with support for the development of key research strategies and direct funding of innovative research projects, including malaria vaccine and drug discovery, that could decrease disease and transmission. Linking research to field operations is a strategy that succeeded for smallpox eradication and will be required for the demise of malaria.
机译:在过去的十年中,对疟疾控制,根除和研究的兴趣和支持大大增加了。这是由于人们对疟疾从地方人群中吸取的巨大医疗,社会和经济负担表示赞赏。药物开发(基于青蒿素的联合治疗),预防性干预(经杀虫剂处理的蚊帐经久耐用),改进的诊断(快速诊断测试)和社区动员方面的最新突破,导致了新动物学工具的部署。由全球抗击艾滋病,结核病和疟疾基金,美国总统的疟疾倡议以及其他捐助者支持的国家计划已经大大降低了疟疾的发病率和死亡率。比尔和梅琳达·盖茨大力推动了根除工作,为关键研究战略的发展提供了支持,并为包括疟疾疫苗和药物发现在内的创新研究项目提供了直接资金,这可以减少疾病和传播。将研究与实地活动联系起来是一项成功根除天花的战略,这对于消除疟疾必不可少。

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