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首页> 外文期刊>Vaccine >The burden of hospitalizations for meningococcal infection in Spain (1997-2008)
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The burden of hospitalizations for meningococcal infection in Spain (1997-2008)

机译：西班牙因脑膜炎球菌感染而住院的负担（1997-2008年）

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摘要

All hospital discharges and deaths related to invasive meningococcal disease, meningococcal meningitis and meningococcemia in the general population from 1997 to 2008 in Spain were obtained. Among the 11,611 meningococcal infection related discharges 53% were meningococcal meningitis and 55% were meningococcemia. The annual hospitalization rate was 2.33, 1.23 and 1.29 cases per 100,000 for invasive meningococcal disease, meningococcal meningitis and meningococcemia, respectively. 846 deaths for invasive meningococcal disease, 235 for meningococcal meningitis and 605 for meningococcemia were reported. Although an important decrease in meningococcal infections related morbidity and mortality has occurred in the last twelve years in Spain, they still continue being major causes of hospitalization and death, especially in the children up to 2 years of age. Future preventive measures, such as vaccination with vaccines covering new conjugated serogroups (B and ACYW135), could further improve population health
机译：获得了西班牙1997年至2008年所有普通人群中与侵袭性脑膜炎球菌病，脑膜炎球菌脑膜炎和脑膜炎球菌血症相关的所有医院出院和死亡信息。在11,611例与脑膜炎球菌感染有关的出院中，53％为脑膜炎球菌性脑膜炎，55％为脑膜炎球菌血症。侵袭性脑膜炎球菌病，脑膜炎球菌性脑膜炎和脑膜炎球菌血症的年住院率分别为每10万人2.33、1.23和1.29例。据报道，侵袭性脑膜炎球菌病有846例死亡，脑膜炎球菌脑膜炎有235例死亡，脑膜炎球菌血症有605例死亡。尽管最近十二年来西班牙脑膜炎球菌感染相关的发病率和死亡率已大大降低，但它们仍继续是住院和死亡的主要原因，尤其是在两岁以下的儿童中。未来的预防措施，例如接种涵盖新的共轭血清群的疫苗（B和ACYW135），可能会进一步改善人口健康

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