Immunogenicity of delayed TBE-vaccine booster.

Askling H. H.; Vene S.; Rombo L.; Lindquist L.

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Immunogenicity of delayed TBE-vaccine booster.

机译：延迟的TBE疫苗加强免疫力。

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Information is scarce regarding the antibody response when TBE-vaccine booster doses are delayed, which is a common situation in daily life. We have investigated the immune response after a delayed booster dose compared to a normal booster interval in an every-day setting. Overall, 250/260 (96%) of the study participants had neutralizing antibodies post-booster, with no significant difference between normal and delayed booster intervals. Based on our findings we propose that healthy individuals who have failed adherence to the recommended schedule of TBE-vaccination can be given a delayed dose without concern of immunogenicity.

机译：当TBE疫苗加强剂量延迟时，关于抗体反应的信息很少，这是日常生活中的常见情况。我们已经研究了在每天的设置中，与正常的加强间隔相比，延迟的加强剂量后的免疫反应。总体而言，250/260（96％）的研究参与者在加强免疫后具有中和抗体，正常间隔时间和延迟间隔时间之间无显着差异。根据我们的发现，我们建议对未能遵循推荐的TBE疫苗接种时间表的健康个体可以延迟剂量服用，而无需担心免疫原性。

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《Vaccine》 |2012年第3期|共4页
作者
Askling H. H.; Vene S.; Rombo L.; Lindquist L.;
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正文语种 eng
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关键词
TBE; Vaccination; Booster dose; Neutralizing antibodies;

机译：TBE;疫苗接种;Booster剂量;中和抗体;

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1. Immunogenicity of delayed TBE-vaccine booster. [J] . Askling H. H., Vene S., Rombo L., Vaccine . 2012,第3期

机译：延迟的TBE疫苗加强免疫力。
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Immunogenicity of delayed TBE-vaccine booster.

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