...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Vaccine >Evaluation of the humoral immune response in adult dairy cattle three years after vaccination with a bluetongue serotype 8 inactivated vaccine.
【24h】

Evaluation of the humoral immune response in adult dairy cattle three years after vaccination with a bluetongue serotype 8 inactivated vaccine.

机译：蓝舌血清型8灭活疫苗接种后三年对成年奶牛的体液免疫反应的评估。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Despite the widespread use of bluetongue serotype 8 (BTV-8) inactivated vaccines across Europe from 2008 to 2011, two very practical questions remain unanswered about the length of persistence of group-specific antibodies in milk and serum post-vaccination and the duration of protection beyond one year post-vaccination. This study has firstly revealed that group-specific antibodies persist at high levels in milk and serum in the majority of cattle for at least 3 years post-vaccination, thus removing the option of using these animals in ELISA-based surveillance programmes. Secondly neutralising antibodies have been shown to persist in the majority of cattle for at least 3 years post-vaccination, indicating that the cattle are likely to be protected for this time period. This extended duration of protection may have contributed towards the rapid and efficient eradication of BTV-8 from many European countries, despite reducing levels of vaccine coverage.Digital Object Identifier http://dx.doi.org/10.1016/j.vaccine.2011.10.100
机译：尽管从2008年到2011年，蓝舌8型血清型（BTV-8）灭活疫苗在欧洲得到广泛使用，但关于牛奶和血清中疫苗接种后组特异性抗体的持续时间长短以及保护期限的问题，仍有两个非常实际的问题尚未得到解答。接种后超过一年。这项研究首先揭示了疫苗接种后至少3年内，大多数牛的牛奶和血清中的组特异性抗体高水平存在，从而消除了在基于ELISA的监测程序中使用这些动物的选择。其次，已证明中和抗体在接种后的至少3年内在大多数牛中持续存在，这表明牛可能在这段时间内受到保护。尽管减少了疫苗覆盖范围，但延长的保护期限可能有助于许多欧洲国家快速有效地根除BTV-8。数字对象标识符http://dx.doi.org/10.1016/j.vaccine.2011.10 .100

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号