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首页> 外文期刊>Vaccine >Burden of human papillomavirus infections and related diseases in the Extended Middle East and North Africa region. (Special Issue: Comprehensive control of HPV infections and related diseases in the extended Middle East and North Africa region.)
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Burden of human papillomavirus infections and related diseases in the Extended Middle East and North Africa region. (Special Issue: Comprehensive control of HPV infections and related diseases in the extended Middle East and North Africa region.)

机译:扩展的中东和北非地区人类乳头瘤病毒感染和相关疾病的负担。 (特刊:全面控制中东和北非地区的HPV感染和相关疾病。)

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摘要

In this chapter, we present the available information on the burden of human papillomavirus (HPV)-related cancers (cancers of the cervix, anogenital cancers, and cancers of the oral cavity and pharynx), as well as available data on the prevalence and distribution of HPV types in women with and without cervical cancer, for the countries of the Extended Middle East and North Africa region (EMENA). The EMENA region is characterized by societies that share similar cultures and religions and that are considered to have a more conservative sexual behaviour compared to Western societies. The incidence of cervical cancer is estimated to be relatively low, although it is difficult to assess precisely because systematic and national cancer registries are lacking in many countries of the EMENA region. In these countries, nationwide programs of cervical cancer screening do not exist or are based on a limited opportunistic cytology-based screening, which often lacks quality assurance. The incidence of anogenital cancers other than cervix is very low. The incidence of cancers of the oral cavity and pharynx is relatively high in some countries, particularly in Pakistan. Relatively low levels of HPV prevalence have been observed in the several surveys conducted in the EMENA region, although only few young women were included in these studies. Possible changes in lifestyle and sexual behaviour in younger generations might, however, change this scenario. Thus, improving the information on the burden of HPV-related cancers and on the HPV prevalence in the general population is essential to develop a comprehensive intervention policy for future management of cervical cancer in this area.
机译:在本章中,我们介绍了与人类乳头瘤病毒(HPV)相关的癌症(子宫颈癌,生殖器癌以及口腔和咽喉癌)的负担的可用信息,以及有关患病率和分布的可用数据中东和北非地区(EMENA)国家中有无宫颈癌的女性中HPV类型的分布EMENA地区的特征是具有相似的文化和宗教信仰的社会,与西方社会相比,被认为具有更保守的性行为。宫颈癌的发病率估计相对较低,尽管由于EMENA地区许多国家缺乏系统的和全国性的癌症登记处,因此难以准确评估。在这些国家中,全国子宫颈癌筛查计划不存在或基于有限的基于机会细胞学的筛查,而这些筛查往往缺乏质量保证。除子宫颈外,肛门生殖器癌的发生率很低。在某些国家,尤其是在巴基斯坦,口腔和咽部癌症的发病率相对较高。在EMENA地区进行的几项调查中,发现HPV患病率相对较低,尽管这些研究只包括了少数年轻妇女。然而,年轻一代生活方式和性行为的可能改变可能会改变这种情况。因此,改善有关普通人群中HPV相关癌症负担和HPV患病率的信息对于制定全面的干预政策,以进一步管理该地区的宫颈癌至关重要。

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