...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Dalton transactions: An international journal of inorganic chemistry >Neutral NCN terdentate luminescent Pt(II) complexes: their synthesis, photophysical properties, and bio-imaging applications
【24h】

Neutral NCN terdentate luminescent Pt(II) complexes: their synthesis, photophysical properties, and bio-imaging applications

机译：中性NCN齿状发光Pt（II）配合物：其合成，光物理性质和生物成像应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

An emerging field regarding N<^>C<^>N terdentate Pt(II) complexes is their application as luminescent labels for bio-imaging. In fact, phosphorescent Pt complexes possess many advantages such as a wide emission color tunability, a better stability towards photo- and chemical degradation, a very large Stokes shift, and long-lived luminescent excited states with lifetimes typically two to three orders of magnitude longer than those of classic organic fluorophores. Here, we describe the synthesis and photophysical characterization of three new neutral N<^>C<^>N terdentate cyclometallated Pt complexes as long-lived bio-imaging probes. The novel molecular probes bear hydrophilic (oligo-) ethyleneglycol chains of various lengths to increase their water solubility and bio-compatibility and to impart amphiphilic nature to the molecules. The complexes are characterized by a high cell permeability and a low cytotoxicity, with an internalization kinetics that depends on both the length of the ethyleneglycol chain and the ancillary ligand.
机译：关于N ^ C ^ N齿状Pt（II）配合物的新兴领域是它们作为生物成像的发光标记的应用。实际上，磷光的Pt配合物具有许多优点，例如宽的发射色可调性，对光和化学降解的更好的稳定性，很大的斯托克斯位移以及长寿命的发光激发态，其寿命通常长两到三个数量级比经典的有机荧光团要强。在这里，我们描述了三种新的中性N ^ C ^ NN齿状环金属化Pt配合物的合成和光物理特征，它们是长寿命的生物成像探针。新型分子探针带有各种长度的亲水性（低聚）乙二醇链，以增加其水溶性和生物相容性并赋予分子两亲性。该复合物的特征在于高细胞渗透性和低细胞毒性，其内在动力学取决于乙二醇链的长度和辅助配体。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号